Protein Alignment Gli and cest-30

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 149/579 - (25%)
• Similarity: 236/579 - (40%)
• Gaps: 142/579 - (24%)

  Fly   178 FLGIPYALPPTFEGRFKPPRVHRGW-QLLQAVDFGPACPQPVRYTGAT--KGIMDMDEDCLYLNV 239
            :||||:|..|....:||.|.....| :.....::||.|||..|:...|  ......:|:||.|||
 Worm    58 YLGIPFAKAPVGALKFKKPVAAEKWTEPRDCYEYGPGCPQTGRFAALTAKSTAAFAEENCLTLNV 122

  Fly   240 YSPKTG-AGVAQKYPVMVYIHGGEFIRGASNLFQGHILAS---FYDVVVVTLNYRLGALGFLSTG 300
            ::|:.. |...:..||:|||:||.:..|.::....:.|..   ..||:|||:|||||.||||:..
 Worm   123 FAPRWKLAEFPKGLPVLVYIYGGGYEIGFTSYMDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIA 187

  Fly   301 DENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQ 365
            |..:.||||:.||.:||:||.|||..|.|:..|:||.|..||..|...|.::|.:..:.:|.|:.
 Worm   188 DGIANGNYGLWDQTLALQWVQDNIASFGGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISM 252

  Fly   366 SGSALADWAL--------------------------IQDKYRAQNTSRVLGQLLGCSIESSWKLV 404
            ||:|..::|:                          :.|.|.|||.|:
 Worm   253 SGTAFCNFAIRPKDVEVGVCKEFAQFQGYTGTDSQSLFDWYMAQNVSK----------------- 300

  Fly   405 NCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHN-FTLPGDDWYEGWREKDWRFLTQTPETLIRAG 468
                    |.|:...: |...|:.|:.|..|.: |..|.|.......:||
 Worm   301 --------FKEVAGFQ-STAAGAVPFIPNFDGDFFPKPFDILRREAPKKD--------------- 341

  Fly   469 KFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYI 533
                  ..:|.||.:.....:......:.|...:| |.::.....|..|         |..:|..
 Worm   342 ------ALITVVTMESVGMIIFNPLFANAYNNFEG-FINETYGPDVTDY---------YADVKKK 390

  Fly   534 YT--FWPDPN--NNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYM----YVLNTTVEALN 590
            .|  :..|.|  :...:..:.::.:||..:.:.....||..::....||:    |..:.|.:.:.
 Worm   391 LTGFYLKDVNASDKATVNRRVVDYVSDSVFNSGTLDAVKSYVKYGNKVYLGSFNYFNDATKDMVE 455

  Fly   591 LPQ-WRKYPH--DIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNP 652
            |.| :::..|  |.:.||.:|   :...|.|..|.::       ..:||...|   .||.:||:|
 Worm   456 LMQPFKEASHSSDFKYYFGSG---VMANFTPTDEEME-------VMDMSGTLM---ANFVKYGDP 507

  Fly   653 T---------PQQVL--GMHFQRAY----------QGEIR-YLNINTTYNSSILLNYRQ 689
            .         |..:|  .|:::..|          .|.:| |.:||.  ||.   .|:|
 Worm   508 NGKSGTKPWKPYTILKPNMYYKIDYPTCEMSDNFQNGRLRIYDDINK--NSK---KYQQ 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	149/579 (26%)
cest-30	NP_504407.1	COesterase	31..539	CDD:278561	140/550 (25%)
		Aes	<122..>230	CDD:223730	47/107 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810