Protein Alignment Gli and cest-19

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 638
• Identity: 179/638 - (28%)
• Similarity: 272/638 - (42%)
• Gaps: 130/638 - (20%)

  Fly   176 SVFLGIPYALPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQ---------PVRYTGATKGIMDM 230
            |||.|||:|:||....||:.|:....|: ::.|..:...|.|         |.||      :..:
 Worm    48 SVFKGIPFAMPPVGYLRFQMPKEPAKWRGVMNATQYSAMCMQNIDENDAGEPERY------VAHV 106

  Fly   231 DEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGA-SNLFQGHILASFYD--VVVVTLNYRLG 292
            .||||||||:||.........|||:|:||||.|..|: |::.|..||::|..  :|.||.|||||
 Worm   107 SEDCLYLNVFSPTPYQYTNDTYPVIVFIHGGRFQTGSGSDIPQRAILSNFVSRKIVFVTFNYRLG 171

  Fly   293 ALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRN 357
            .|||.||||...|||.|:.||..||:||..|.|.|.||.::|.|.|.|.|.|||.||.::|:...
 Worm   172 PLGFASTGDSVLPGNIGLWDQIWALKWVKANAEVFGGDPSNILLMGHGTGAASASLLALSPRAEG 236

  Fly   358 IVRRVIAQSGSAL-----------ADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCL--RT 409
            :.::|:..|||||           |.|.: .|::             ||...:|.:|::|.  |:
 Worm   237 LFQKVLLMSGSALQPGVVRNTQVNATWNM-NDRF-------------GCRAFNSSELLDCARKRS 287

  Fly   410 GRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPE--TLIRAGKFNR 472
            ....::.....|.            |:...:|..|...|       .|.:.||  ||.|     |
 Worm   288 KEEIFQYKRLHFD------------DYEEFVPIIDGVGG-------ILPEPPEQLTLHR-----R 328

  Fly   473 NIQYMTGVTTQEAAFFV---------------AQNESLSPYYELDGRFFDQKIREHVFRYNYTLN 522
            ....:.|.|..|::..:               ...|:|:....|..:.|.          |:.|.
 Worm   329 KTPIVIGTTKDESSLRILLLNEKDLNFSSITWENGETLADNLTLGFKQFQ----------NHRLI 383

  Fly   523 PNGVYEAIKYIYTFWPDPN-NNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTV 586
            ..|...  :|::| ..||: ..:::.:..:.|.|..:|.||..|:....|:..:|||:|..:...
 Worm   384 SQGCKS--EYVWT-QVDPSFPESVLFNSLLKMYSHFWYDAPASQLATYYLKHDLPVYLYSFDHIS 445

  Fly   587 EALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGN 651
            |..         :||:|.|............|:..:.:::|....|:.:...|.:...|||.||.
 Worm   446 ENF---------YDIDRAFHGVDKLHIFNVTPRFLNKRKDMNWQLDQRVVEIFSELVANFALYGT 501

  Fly   652 PTPQ-QVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVIGVLVPTYPPTTE 715
            ||.: .....::......|:.||:|  |.:.|:.:.||.....||..|..::..|.|.......:
 Worm   502 PTHENDGFSFNWTSTTAKELSYLSI--TDSPSMQVGYRWQGHVFWNWYARSLDAVDVGNIQRIAQ 564

  Fly   716 YWWEPKEPLQIAFWSMSVA----C--FFLIVLVVICCIMWRNAKRQSDRFYDE 762
            .      ...:..|..:.|    |  ||..:||.:.|...|   ::||.  ||
 Worm   565 L------DRDVGNWQFATAMLSFCSLFFFAILVGLACYCTR---KESDE--DE 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	161/563 (29%)
cest-19	NP_509187.4	Abhydrolase	27..544	CDD:389770	161/563 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770