Protein Alignment Gli and cest-2.1

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 577
• Identity: 136/577 - (23%)
• Similarity: 228/577 - (39%)
• Gaps: 113/577 - (19%)

  Fly   178 FLGIPYALPPTFEGRFKPPRVHRGWQ-LLQAVDFGPACPQPVR--YTGATKGIMDMDEDCLYLNV 239
            |||||:..||....||:.||....|. :|:..::.|||....:  |.....|  .:.|||||.||
 Worm    48 FLGIPFVEPPAGNLRFRKPRPPIPWDGILETKEYKPACMSDAKKTYKNGVGG--PISEDCLYANV 110

  Fly   240 YSPKTGAGVAQKY-------PVMVYIHGGEFIRGASNLFQGHILASFY-----DVVVVTLNYRLG 292
            ::        .:|       .||:.:|||..:..:::.|...||.:.:     ::||||.|||||
 Worm   111 FT--------NQYCMKRKNCSVMIVVHGGRILTESASAFNPEILVNNFVGQGRNIVVVTFNYRLG 167

  Fly   293 ALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRN 357
            ..||.....|....|.|:.|...|::|....:..|.|:::.:|:.|..|||:..|....:|.::.
 Worm   168 TFGFGVLNGEKGDSNVGMFDMLEAVKWTRKEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSPLSKG 232

  Fly   358 IVRRVIAQSGSALADWALIQ-DKYRAQNTSRVLGQLLGCSIE-SSWKLVNCLRTGRSFYELGNAE 420
            ::.:.|..||      ||.| .|.........:.|..||..| ..::.::.:|..:::..|.|
 Worm   233 MLNQQIIMSG------ALYQMGKLANFKGMTAMAQKAGCLPEVFGFRKLSQVRIDKTYSCLRN-- 289

  Fly   421 FSPQVGSFPWGPVLDHN-FTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQE 484
            .|.|       .|||.. :.|....:|......|..||....:.::.:|..: .|..|.|.||.|
 Worm   290 ISAQ-------EVLDAQLWVLQNTTYYISVPHIDGEFLLNYSDEILASGTIH-PINSMIGTTTAE 346

  Fly   485 AAFFVAQNESLSPYYELDGRFFDQK------IREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNN 543
            ..         .|.|..|.:..|:|      :.||:....|| .|.   |..:....|:.:.::.
 Worm   347 LR---------DPIYINDLKNADKKEELLKNLCEHIGYELYT-EPE---EFSRKCQKFYGNGDDA 398

  Fly   544 TIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKY-----PHDIE- 602
            ..:.|       |:.:.....::......:...|:||..:.....   |.::||     ||..|
 Worm   399 QFLAD-------DMEFYDGSIKVANAHASKNTKVFMYSYDYKDAG---PAFKKYAQAPPPHHSED 453

  Fly   603 RYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQ 667
            ..::.|.              .|..:|:.|..:...:...:.:|..:|||:|.:   ....:.|.
 Worm   454 LIYVFGT--------------SRGNFTEKDYVIEQIYSGMFADFVNFGNPSPSK---EQKWKEYS 501

  Fly   668 GEIR-YLNINTTYNSSI---LLNYRQTECAFWT---------QYLPTV----IGVLV 707
            .|.| |..|:...|.::   ...|......||:         .|.|::    .|:|:
 Worm   502 PEKREYFLIDFDKNFTMPGTRDGYYSRALEFWSTAGTKSFSEHYSPSLDSFTTGILI 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	130/550 (24%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	130/550 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28602
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780