Protein Alignment Gli and ges-1

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_503411.1
• Gene: ges-1 / 178633
• WormBaseID: WBGene00001578
• Length: 562
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 168/601 - (27%)
• Similarity: 264/601 - (43%)
• Gaps: 123/601 - (20%)

  Fly   137 VTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRG 201
            |.||||:|:|.:   |:..:                    |||.||:|.||..:.||:.|.....
 Worm    20 VETNYGKVEGIE---YEGAE--------------------VFLAIPFAKPPVDDLRFEKPVAPDP 61

  Fly   202 WQ-LLQAVDFGPACPQPVR-------YTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYI 258
            |: :..|..:...|....|       |:|         ||||.||:..||.    |:|.||:.:|
 Worm    62 WEDVYPATQYRNDCTPHYRLVAQFSSYSG---------EDCLTLNIIKPKK----AEKLPVLFWI 113

  Fly   259 HGGEFIRGASNLFQGHILASFY---DVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWV 320
            |||.:..|:::.......|..|   .|:|.|:.||||.:||.|.|..:..||:|:.|||.||.:|
 Worm   114 HGGGYEIGSASQHGYEFFAKRYASQGVIVATVQYRLGFMGFFSEGTSDVQGNWGLFDQAAALEFV 178

  Fly   321 YDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNT 385
            ..|||.|.||.|.||::|..||.||...|.::|.||:...:.|..|.|:...||...:   ...|
 Worm   179 KSNIENFGGDPNQITIWGYSAGAASVSQLTMSPYTRDSYSKAIIMSASSFVGWATGPN---VVET 240

  Fly   386 SRVLGQLLGCSIESSWK-LVNCLRTGRSFYELGNA-----EFSPQVGSFPWGPVLDHNFTLPGDD 444
            |:.|.::|||    .|. ...|::. :|.:|:.:|     ..:..:....|.||:|      ||
 Worm   241 SKQLAEILGC----PWPGAKECMKK-KSLHEIFDAIEVQGWTTGTIDILRWSPVID------GD- 293

  Fly   445 WYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNE-------SLSP--YYE 500
                       |:|:.||.||:.......   :.|::.:|.::|.|.|.       .|||  ..:
 Worm   294 -----------FMTKNPEELIKESPVKPT---LIGMSNKEGSYFAALNMGRVIADFGLSPEDMPK 344

  Fly   501 LDGRFFDQKI-REHVFRYNYTLNPNGVYEAIKYIYTFWPDP----NNNTIIRDQYINMLSDLYYR 560
            :|..|..:.| |:.::...|..|...|:..|...|.....|    :.|....|:|..:|||:.:.
 Worm   345 VDEEFISEIIGRKLLYNNRYGENREKVWNDILDFYVKQGKPAEVKDLNGFYVDRYSELLSDITFN 409

  Fly   561 APVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKY--------PHDIERYFLTGAPFMDTEFF 617
            .|:.:.:...:|:|.||:.|.::...:.:    |:|:        ||..|.::|...|.| .:..
 Worm   410 VPILREITSRVERKTPVWTYRMDHYDKNI----WKKHIPEQARGSPHANEYHYLFDMPVM-AKID 469

  Fly   618 PKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQ-GEIRYLNINTTYNS 681
            .|||   .:.|..||      .:....:||:.|.|   |:..:.::.... .::.:|||.:. ..
 Worm   470 MKKE---PDSWIQND------LIDMVISFAKTGVP---QIEDVEWRPVSDPDDVNFLNIRSD-GV 521

  Fly   682 SILLNYRQTECAFWTQ 697
            ||.....|...|||.:
 Worm   522 SIEHGLFQEPLAFWNE 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	166/597 (28%)
ges-1	NP_503411.1	COesterase	18..535	CDD:278561	166/597 (28%)
		Aes	<100..>211	CDD:223730	48/114 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167723
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740