Protein Alignment Gli and cest-10

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 131/602 - (21%)
• Similarity: 218/602 - (36%)
• Gaps: 164/602 - (27%)

  Fly   135 VFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVH 199
            |.|.|:.|::.|.::                       |...:|..||:|.||..:.||:.|:..
 Worm    22 VIVETSLGKLNGDQI-----------------------GNFHLFKKIPFAKPPLGKLRFQKPQPA 63

  Fly   200 RGWQ-LLQAVDFGPACPQPVRYTGATKGIMD-MDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGE 262
            ..|. :..|.|:||||   :..:..||.:.. :|||||:||:::.:| ...::...|::|:|||.
 Worm    64 ETWNGVRNAKDYGPAC---MSNSSTTKTVQKWVDEDCLHLNIFTSET-CLKSKNCAVVIYLHGGN 124

  Fly   263 FIRGASNLFQGHILASFY---DVVVVTLNYRLGALGFLSTGDEN-SPGNYGILDQAMALRWVYDN 323
            ....::.:|....|...|   ::|.|....|||........|:: :|.|..:.|...|:.:...:
 Worm   125 LHYDSAVMFNDTFLLHTYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQAMEFAKSD 189

  Fly   324 IEFFNGDRNSITLFGPGAGGASAGLLMVAPQTR---NIVRRVIAQSGSALADWALIQ-------- 377
            |..|.|:....||.|...||..|.:|..:.:..   ::.::.|:.|.....|...:|
 Worm   190 IHNFGGNNKRTTLLGHSYGGTVASMLSFSTKVNTDLSLFQQYISMSSPTNFDTLELQVERTYRFA 254

  Fly   378 ---------DKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPV 433
                     .|:..:|...|  .:..|..:.|  ....||..||..|.|...:.   ||...||:
 Worm   255 EHANCLPKNSKFMRKNQKEV--YMRDCLKKKS--ASELLRIQRSLEEAGYPVYG---GSVMRGPI 312

  Fly   434 LDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPY 498
                        ::...|:|:   ..:|          .||..:||.|..|:..:        .:
 Worm   313 ------------FQEVLERDF---MDSP----------NNITSLTGCTKYESLVY--------DH 344

  Fly   499 YELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYIN----MLSDLYY 559
            |...|:....:..|.|         |..|.:         |.....|..|...|    ||..:..
 Worm   345 YRNMGKALGFENYEEV---------NEKYRS---------DSKEGKIEFDNVKNATQIMLIQIRT 391

  Fly   560 RAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYP----HDIERYFLTGA-PFMDTEFFPK 619
            |      |..:|::.:|.|.|..             .||    |..:.:|:.|. ||:..|
 Worm   392 R------VNKILKKNIPAYHYEY-------------AYPKHANHTDDLFFIMGVHPFIQDE---- 433

  Fly   620 KEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNIN---TTYNS 681
                       |:..:.:|:...:.||.:.|||      |.....|......|..:|   ||...
 Worm   434 -----------NEIKLGNFYRSMFLNFIKTGNP------GNGCDGANLNGSTYFEVNWNETTGER 481

  Fly   682 SILL-NYRQTECAFWTQ 697
            .::. |:.|....:||:
 Worm   482 PVMKNNFEQKILDYWTK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	129/598 (22%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	130/601 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900