Protein Alignment Gli and Nrt

DIOPT Version :10

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: XP_061499238.1
• Gene: Nrt / 1276329
• VectorBaseID: AGAMI1_007617
• Length: 892
• Species: Anopheles gambiae
• Alignment Length: 639
• Identity: 156/639 - (24%)
• Similarity: 225/639 - (35%)
• Gaps: 211/639 - (33%)

  Fly   126 RDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFE 190
            ||...:|    ..||.|:|:|..       :..||                .|.|||||:||...
Mosquito   407 RDGKYIE----TVTNCGRVEGIL-------EDGSF----------------AFRGIPYAVPPVGP 444

  Fly   191 GRFKPPR----VHRGWQ-LLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQ 250
            .|:|..:    :...|. .|:|.:..|.|.|..     ..|.:|..||||.|:|.:|..
Mosquito   445 NRWKAAQPIESIENCWNGTLKAHNSTPVCWQIY-----ADGKVDGAEDCLTLDVITPHV------ 498

  Fly   251 KY----PVMVYIHGGEFIRGAS--NLFQGHILASFYDVVVVTLNYRLGALGFLS----TGDENSP 305
            :|    ||:|.: |.|...|.|  .|......|...||:.|..|:||...|||:    |...:.|
Mosquito   499 RYDNPLPVVVLV-GAESFTGDSPGKLRPSTRYARARDVIFVRPNFRLNVFGFLALEQLTKSTHPP 562

  Fly   306 --GNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGS 368
              ||||:.|..:||:|:..||..|.||..|:||||..|||.....|..:.:|..:..|....||:
Mosquito   563 TSGNYGLTDLIVALKWIQLNIPHFGGDPKSVTLFGHRAGGTIVTALASSNKTSKLFARTWISSGA 627

  Fly   369 AL----------ADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSP 423
            |:          .:.||...|.|.:::                   |||.. :...|:.:|  .|
Mosquito   628 AIFPGNPLAESEKENALYMSKIRCEDS-------------------NCLME-KEDEEILDA--VP 670

  Fly   424 QV--GSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAA 486
            .|  .:||..|..|.|.|...:     |...|...:.|.|..:..|...| |::|:.|.||.|
Mosquito   671 DVWRRTFPDLPAADENATARHE-----WLVLDGNIMQQHPADVWSADVSN-NVRYVIGSTTHE-- 727

  Fly   487 FFVAQNESLSPYY-----ELDGRFFDQKI-------REHVFRYNYTLNPNGVYEAIKYIYTFWPD 539
               |.|..|...|     ||..|..::.:       .|.:.|||.|      |:.:
Mosquito   728 ---AHNTKLHLKYTEWTPELVTRHVNESVVGRLGLTEEALRRYNAT------YQGL--------- 774

  Fly   540 PNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKV-PVYMYVLNTTVEALNLPQWRKYPHDIER 603
                       :.|:||:....|:     |.:.||: ....||::.|...|.:..
Mosquito   775 -----------VAMVSDIRTICPL-----LTITQKLQSSQFYVVSQTGGELGIAD---------- 813

  Fly   604 YFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQ------VLGMHF 662
                                     .|:|         ......||...||:|      :..:.:
Mosquito   814 -------------------------VDSD---------VQAILGRYEPKTPEQRRYVSAIQQLFY 844

  Fly   663 QRAYQGEIRY------LNINTTYNSSILLNYRQTECAFWTQYLPTVIGVLVPTY 710
            .....|||::      |:|    ....|..|....|.||      :...:||.|
Mosquito   845 HYVSHGEIKHELRKKLLDI----GQDALPTYNTDNCLFW------IKNDVVPRY 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	137..695	CDD:395084	148/611 (24%)
		PRK13335	818..>918	CDD:139494
Nrt	XP_061499238.1	None