Protein Alignment Gli and Ces1g

DIOPT Version :9

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 573
• Identity: 168/573 - (29%)
• Similarity: 258/573 - (45%)
• Gaps: 92/573 - (16%)

  Fly   165 HSTVDRVMGE----------CSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQ-AVDFGPACPQPV 218
            |:...:|:|:          .:||||:|:|.||....||.||.....|..:: ...:.|.|.|..
Mouse    27 HTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRFAPPEPAEPWSFVKHTTSYPPLCYQNP 91

  Fly   219 R--------YTGATKGI-MDMDEDCLYLNVYSPKTGAGVAQ--KYPVMVYIHGGEFIRGASNLFQ 272
            .        :|...|.| ....|||||||:|:|   |.:.|  :.||||:||||..:...::.:.
Mouse    92 EAALRLAELFTNQRKIIPHKFSEDCLYLNIYTP---ADLTQNSRLPVMVWIHGGGLVIDGASTYD 153

  Fly   273 GHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLF 337
            |..||...:||||.:.||||..||.||.||:|.||:|.|||..||.||.|||..|.|:..|:|:|
Mouse   154 GVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLDQVAALHWVQDNIANFGGNPGSVTIF 218

  Fly   338 GPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWK 402
            |..|||.|..:|:::|..:|:..|.|||| |.:.:..|.  ...|:..::.:..|.||...:|..
Mouse   219 GESAGGESVSVLVLSPLAKNLFHRAIAQS-SVIFNPCLF--GRAARPLAKKIAALAGCKTTTSAA 280

  Fly   403 LVNCLR--TGRSFYEL------GNAEF--SPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFL 457
            :|:|||  |.....|:      |..:|  .|: .|:|:.|.:.....||
Mouse   281 MVHCLRQKTEDELLEVSLKMKFGTVDFLGDPR-ESYPFLPTVIDGVLLP---------------- 328

  Fly   458 TQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPY---YELDGRFFDQKIREHVFRYNY 519
             :.||.::....|| .:.||.|:...|..:.:       |.   :.|..|..|||....:....|
Mouse   329 -KAPEEILAEKSFN-TVPYMVGINKHEFGWII-------PMFLDFPLSERKLDQKTAASILWQAY 384

  Fly   520 ---TLNPNGVYEAIKYIYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYM-- 579
               .::...:..||:.......||...|   |.:::::.|:.:..|...:.:...:...|.||
Mouse   385 PILNISEKLIPAAIEKYLGGTEDPATMT---DLFLDLIGDIMFGVPSVIVSRSHRDAGAPTYMYE 446

  Fly   580 YVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYT 644
            |....:..:.:.||.....|..|.:.:.||||:       ||..     ::.:.|:|...|:.:.
Mouse   447 YQYRPSFVSDDRPQELLGDHADELFSVWGAPFL-------KEGA-----SEEEINLSKMVMKFWA 499

  Fly   645 NFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQ 697
            ||||.|||..:   |:.....|..:..||.|.....::..|  :..|..|||:
Mouse   500 NFARNGNPNGE---GLPHWPEYDQKEGYLQIGVPAQAAHRL--KDKEVDFWTE 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	134..695	CDD:278561	165/569 (29%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	165/569 (29%)
		Aes	<121..>239	CDD:223730	55/120 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832559
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740