Protein Alignment Gli and ces2

DIOPT Version :10

• Sequence 1: NP_476602.1
• Gene: Gli / 34927
• FlyBaseID: FBgn0001987
• Length: 956
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces2 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 175/593 - (29%)
• Similarity: 270/593 - (45%)
• Gaps: 97/593 - (16%)

  Fly   139 TNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGW- 202
            |.|||:.|..|...:              .||::   .||:|:|:|.||....||:.|:....|
 Frog    29 TKYGQLLGKTVGAKE--------------TDRLV---HVFMGVPFAKPPIGPLRFEAPQPPEPWS 76

  Fly   203 QLLQAVDFGPACPQPVRYTGATKGIMDM--------------DEDCLYLNVYSPKTGAGVAQKYP 253
            .:.:|....|.|.|       .|.:|::              .||||||||::| ...|.....|
 Frog    77 SVREATAPSPMCLQ-------DKEVMELLADFFKAKFDFSRVSEDCLYLNVFTP-ADKGENPGLP 133

  Fly   254 VMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALR 318
            |||:||||....|.:::|:|..|:::.:||||::.||||.:|||||||:...||:|.|||..||:
 Frog   134 VMVFIHGGGLAIGGASMFEGSALSAYENVVVVSIQYRLGIMGFLSTGDKEVRGNFGFLDQVAALQ 198

  Fly   319 WVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQ 383
            ||.|||:.|.||..|:|:||..|||.|...|:::|.:..:..|.||:||.|      |.....|.
 Frog   199 WVRDNIKDFGGDPQSVTIFGESAGGLSVSALVLSPLSEGLFHRAIAESGVA------ILPGLTAS 257

  Fly   384 NTSRVLGQL------LGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPG 442
            .|..:|..|      ..||:..   ||.||: .::..|:.....:.:...||  .|:|..| ||
 Frog   258 KTEEILPLLDMVINVSSCSVSD---LVGCLK-NKTEDEIIEITAAMRYVIFP--AVVDGVF-LP- 314

  Fly   443 DDWYEGWREKDWRFLTQTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFD 507
                             .|...|.|.|.:..:.::.|:...|....:....:::.|.|    ..:
 Frog   315 -----------------KPAEEILAAKESHPVPFLIGINNHEFGSMLPVTLNITGYRE----GME 358

  Fly   508 QKIREHVFRYNYTLNPNGVYEAIKYIY-TFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLML 571
            :|..:.:......||.  |...|.:|. .::.|.|:...:|:.::::..|:.:..|..:..|...
 Frog   359 KKDIQAILGALPLLNT--VSSVIPFIMEEYFGDTNDPKELRNNFLDLAGDIIFVIPALRTAKYHR 421

  Fly   572 EQKVPVYMYVL--NTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRN 634
            :...|||.|..  ..::.|.:...:.|..|..|.||:.|.||:      |...|.::..|:.::.
 Frog   422 DSGFPVYFYEFQHRPSLYADSKEDFVKADHGDELYFVGGGPFL------KNGILFKSNGTEEEKI 480

  Fly   635 MSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYL 699
            :|...|:.:.||||.|:|...   |:.....|..:..||.||.|..||..|...:.|  |||..|
 Frog   481 LSKTIMKYWANFARNGDPNGH---GLAEWPKYDEDEDYLEINLTQKSSQRLKGERFE--FWTITL 540

  Fly   700 PTVIGVLV 707
            |..|..|:
 Frog   541 PDKIQKLM 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gli	NP_476602.1	COesterase	137..695	CDD:395084	168/579 (29%)
		PRK13335	818..>918	CDD:139494
ces2	NP_001120019.1	COesterase	25..536	CDD:395084	168/579 (29%)