Protein Alignment CycE and CCNB3

DIOPT Version :9

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_016885402.1
• Gene: CCNB3 / 85417
• HGNCID: 18709
• Length: 1404
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 112/452 - (24%)
• Similarity: 175/452 - (38%)
• Gaps: 82/452 - (18%)

  Fly   121 NEDP----ELGF-------EPPSAKRQQRLPALYGSEQG---NLSSVA-------SSVYTSPVVS 164
            ||.|    ||.|       |.|:.|....|..|...:.|   |:||.|       ||:.|...|.
Human   934 NEKPTTGKELSFKEPLALQESPTYKEDTFLKTLLVPQVGTSPNVSSTAPESITSKSSIATMTSVG 998

  Fly   165 VDGQST-----QELLSIRSSPAEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVVVRYAAEQVVTST 224
            ..|...     ::::::...|......:...||. ..:||...:....:|.::.:......|.||
Human   999 KSGTINEAFLFEDMITLNEKPTTGKELSFKEPLA-LQESPTCKEDTFLETFLIPQIGTSPYVFST 1062

  Fly   225 VVTQKTEDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLP 289
            .....||...:...:....|....:....|...|      ..:||.:.|..::|.     ||
Human  1063 TPESITEKSSIATMTSVGKSRTTTESSACESASD------KPVSPQAKGTPKEQI-----TP--- 1113

  Fly   290 KHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRD-EQDSRLRSISM 353
              :|.|....||...|   ||                   .|.:::..|..|: |:.::.....:
Human  1114 --REDIDEDSSDPSFN---PM-------------------YAKEIFSYMKEREIEETAQSHEQFI 1154

  Fly   354 LEQHPGLQ----PRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGIT 414
            |..:...|    ..|||||:|||:||...:::..||.||||..:|.||..| ..:|..|||:|.|
Human  1155 LTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKA-VCKKDKLQLLGAT 1218

  Fly   415 CLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQ-LNV 478
            ...:|||.||...|::.:|.|:.|......::|:.|..:|..|..||:......:|..|.: ::.
Human  1219 AFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIHT 1283

  Fly   479 NNRTPASFSQIGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVG-----MANYS-YSV 534
            |.:|......|......|    :.|.|....:....|.||.|....:|     :.:|| ||:
Human  1284 NMKTLTLSRYICEMTLQE----YHYVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSI 1341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	45/133 (34%)
		Cyclin_C	<517..>571	CDD:281044	8/24 (33%)
CCNB3	XP_016885402.1	Cyclin_N	1133..1266	CDD:306612	45/133 (34%)
		Cyclin_C	1268..1384	CDD:308564	17/78 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820