DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycE and CYCB2;4

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001323249.1	Gene:	CYCB2;4 / 843964	AraportID:	AT1G76310	Length:	459	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	109/487 - (22%)
Similarity:	186/487 - (38%)	Gaps:	148/487 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 EQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSSPAEDLSEAPHSPL----PDSPDS-------P 199
            :||.|..       ..|:..:||:.:.|.:|.    :::..||..|.    |.:..:       |
plant    18 QQGGLRG-------GKVIPTNGQTRRALSNIN----KNIIGAPVYPCAVKRPFTEKNGICNKKIP 71

  Fly   200 PSPDRGSKQTPVVVRYAAEQVVTSTVV-TQKTEDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIY 263
            |.|    ...||..::||:....:..: .::|:..||:.:...|....:.:|.|..|
plant    72 PVP----VHRPVTRKFAAQLAENNLQIHKEETKKPDLISNEALDRIITDVEEGDFNE-------- 124

  Fly   264 SSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVSDLM-INMR--TPMSPAVENGL------- 318
                                  |...:|.|.:...:..:. |.|:  ..:...||..:
plant   125 ----------------------PMFVQHTEAMLEEIDKMEGIEMQDSNDIDAEVEESVMDIDSCD 167

  Fly   319 RQCPLPALAWANAADVWRLMC--HRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKL 381
            :..||..:.:.|  |::   |  .::|..|.:....|..|| .:..|||.||.||||||...::|
plant   168 KNNPLSVVEYIN--DIY---CFYKKNECRSCVPPNYMENQH-DINERMRGILFDWLIEVHYKFEL 226

  Fly   382 HRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEFAYVTDGACTERDI 446
            ..||.||.::.:||:|.|...:.:..|||:|:|.:.:|.|.||:..|.:.:...::|.|.|..:|
plant   227 MEETLYLTINLIDRFLAVHQHIARKKLQLVGVTAMLLACKYEEVSVPVVDDLILISDKAYTRTEI 291

  Fly   447 L-------------NH---------------EKILLQALDWDISPITITGWLGVYMQLNVNNRTP 483
            |             ||               ||::...|                 |.|....||
plant   292 LDMVKSFTKSCPDYNHGCSALYVDDHYCVLQEKLMANTL-----------------QFNFCLPTP 339

  Fly   484 ASFSQIGRQ--KSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSR 546
            ..|.   |:  |:|::|.......|.         :::||.::..|..|:.|.|||:||   ::.
plant   340 YVFM---RRFLKAAQSDKKLELLSFF---------MIELCLVEYEMLQYTPSQLAASAI---YTA 389

  Fly   547 EMALR-----------CSGLDWQVIQPCARWM 567
            :..|:           .||...:.:..|:|.|
plant   390 QSTLKGYEDWSKTSEFHSGYTEEALLECSRKM 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	47/158 (30%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044	16/62 (26%)
CYCB2;4	NP_001323249.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920