DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycE and CYCA3;4

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_973983.1	Gene:	CYCA3;4 / 841126	AraportID:	AT1G47230	Length:	370	Species:	Arabidopsis thaliana

Alignment Length:	511	Identity:	116/511 - (22%)
Similarity:	193/511 - (37%)	Gaps:	185/511 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 DSQNLAASTAATSNGNKRKRRLSS---DSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASS 156
            ::||.|..|.|.:     ||:.||   |.|        |.|.||     .:.| |..|:|:
plant     3 ENQNCARMTRAAA-----KRKASSMALDEN--------PVSKKR-----VVLG-ELPNMSN---- 44

  Fly   157 VYTSPVVSVDGQSTQEL---LSIRSSPAEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVVVRYAAE 218
                 ||:|..|..:.|   .|:.:|                       .|..|:..::..
plant    45 -----VVAVPNQERETLKAKTSVNTS-----------------------KRQMKKALMIPE---- 77

  Fly   219 QVVTSTVVTQKTEDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGE 283
               .|.::..::.|..:    ||.:                          ||..|:..:.:.|:
plant    78 ---ASVLIESRSVDPQM----CEPF--------------------------ASDICAYLREMEGK 109

  Fly   284 RTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRL 348
                 |||:                             |||                  :...::
plant   110 -----PKHR-----------------------------PLP------------------DYIEKV 122

  Fly   349 RSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGI 413
            :|        .|.|.|||:|:|||:||.|.|||..:|.||.:.|:||:|.| ..:.:..|||:|:
plant   123 QS--------DLTPHMRAVLVDWLVEVAEEYKLVSDTLYLTISYVDRFLSV-KPINRQKLQLVGV 178

  Fly   414 TCLFVAA-KVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLN 477
            :.:.:|: |.|||.|||:.:|.|:||...|::::::.|..:|.||.:::...||..:|
plant   179 SAMLIASRKYEEIGPPKVEDFCYITDNTFTKQEVVSMEADILLALQFELGSPTIKTFL------- 236

  Fly   478 VNNRTPASFSQIGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISH 542
                         |:.:..|.:.|...|.. .||: ...|.:|..||.....|..|:|:|:|:
plant   237 -------------RRFTRVAQEDFKDSQLQ-IEFL-CCYLSELSMLDYTCVKYLPSLLSASAV-- 284

  Fly   543 TFSREMALRCSGLDW-QVIQPCARWMEPFFRVISQKAPYLQLNEQN---EQVSNKF 594
             |.....:|.....| |:::...::.....:|.......|.|:.:.   |.|.||:
plant   285 -FLARFIIRPKQHPWNQMLEEYTKYKAADLQVCVGIIHDLYLSRRGNTLEAVRNKY 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	45/129 (35%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044	13/54 (24%)
CYCA3;4	NP_973983.1	Cyclin_N	98..228	CDD:278560	53/190 (28%)
CYCA3;4	NP_973983.1	Cyclin_C	230..353	CDD:281044	29/135 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920