DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycE and CYCA2;3

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_173010.1	Gene:	CYCA2;3 / 838127	AraportID:	AT1G15570	Length:	450	Species:	Arabidopsis thaliana

Alignment Length:	497	Identity:	116/497 - (23%)
Similarity:	190/497 - (38%)	Gaps:	159/497 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 SFSSASQRSEEELPGTSAASRTDEMCSCDSQNLAASTAATSNGNKRKRR--LSSDSNEDPELGFE 129
            |.:||.:.||       ..|.|......:::..|......:..||||:|  |...:|.:.....
plant    14 SLASALRASE-------VTSTTQNQQRVNTKRPALEDTRATGPNKRKKRAVLGEITNVNSNTAI- 70

  Fly   130 PPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSSPAEDLSEAPHSPLPD 194
             ..||..:::....|....:.|.:|:|| ||.|..:..: |...:.:.|:.|.:||.:
plant    71 -LEAKNSKQIKKGRGHGLASTSQLATSV-TSEVTDLQSR-TDAKVEVASNTAGNLSVS------- 125

  Fly   195 SPDSPPSPDRGSKQTPVVVRYAAEQVVTSTVVTQKTEDDDLLDDSCEDYSYDEDDEDDVEEEDDD 259
                     :|:..|.                           |:|
plant   126 ---------KGTDNTA---------------------------DNC------------------- 135

  Fly   260 VEIYSSTISP----ASSGCSQQQAVNGERT-PGLPK----------------HQEQIHHPVSDLM 303
            :||::|.:.|    .|:..:::.||.|..| |.:||                :..:||:
plant   136 IEIWNSRLPPRPLGRSASTAEKSAVIGSSTVPDIPKFVDIDSDDKDPLLCCLYAPEIHY------ 194

  Fly   304 INMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAIL 368
             |:|.       :.|::.|||.            ...|.::|              :...||.||
plant   195 -NLRV-------SELKRRPLPD------------FMERIQKD--------------VTQSMRGIL 225

  Fly   369 LDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEF 433
            :|||:||.|.|.|..:|.||.|..:|.:|| .:.||:..|||:||||:.:|:|.|||..|:|.||
plant   226 VDWLVEVSEEYTLASDTLYLTVYLIDWFLH-GNYVQRQQLQLLGITCMLIASKYEEISAPRIEEF 289

  Fly   434 AYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGRQKSAEAD 498
            .::||...|...:|..|..:|:                 :....:...||.:|.   |:....|.
plant   290 CFITDNTYTRDQVLEMENQVLK-----------------HFSFQIYTPTPKTFL---RRFLRAAQ 334

  Fly   499 DAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAI 540
            .:.:.|... .||: .|.|.:|..:|.....:..||:||:|:
plant   335 ASRLSPSLE-VEFL-ASYLTELTLIDYHFLKFLPSVVAASAV 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	45/128 (35%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044	8/24 (33%)
CYCA2;3	NP_173010.1	CYCLIN_AtCycA_like_rpt1	181..316	CDD:410265	53/192 (28%)
CYCA2;3	NP_173010.1	CYCLIN_AtCycA-like_rpt2	320..434	CDD:410210	17/60 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920