DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycE and CYCA2;1

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001332473.1	Gene:	CYCA2;1 / 832610	AraportID:	AT5G25380	Length:	443	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	112/529 - (21%)
Similarity:	214/529 - (40%)	Gaps:	131/529 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 AATSNGNKRKRRLSSDSNEDPELGFEPPSAK-----RQQRLPALYGSEQGNLSSVASSVYTSPVV 163
            |::.:.|.:|..:|:....|..:......||     .....|| :..|...::..::....|..:
plant     4 ASSKHTNAKKEAISTSKIRDNNVRVTRSRAKALGVSNSPSKPA-FKHETKRVARPSNKRMASDNI 67

  Fly   164 SVDGQSTQELLSIRSSPAEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVVVRYAAEQVVTSTVVTQ 228
            :|..|..:.:|       :|::......:..:..:..:..||.|:                  |:
plant    68 TVCNQKRRAVL-------KDVTNTLAESIISTEGNVKACKRGGKE------------------TK 107

  Fly   229 KTEDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQE 293
            :.|:|.|:|        .:.::..:.|:...:.:..|    ..:..|:|:.|:         ..|
plant   108 QIEEDGLVD--------VDGEKSKLAEDLSKIRMVES----LDASASKQKLVD---------CAE 151

  Fly   294 QIHHPVSDLMINMRTPMSPAVENGLRQ---CPLPALAWANAADVWRLMCHRDEQDSRLRSISMLE 355
            :....|:|.:      ....:::|::.   |.|.|.:..::.:|       .|.:.|..:..|::
plant   152 EDRSDVTDCV------QIVDIDSGVQDPQFCSLYAASIYDSINV-------AELEQRPSTSYMVQ 203

  Fly   356 QHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHK-VQKTHLQLIGITCLFVA 419
            ....:.|.||.||:|||:||.|.|||..:|.||.|:.:||::  :|. ::|..|||:||||:.:|
plant   204 VQRDIDPTMRGILIDWLVEVSEEYKLVSDTLYLTVNLIDRFM--SHNYIEKQKLQLLGITCMLIA 266

  Fly   420 AKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPA 484
            :|.|||..|::.||.::||...|..::|:.|..:|.:|.:.:|..|...:|..::
plant   267 SKYEEISAPRLEEFCFITDNTYTRLEVLSMEIKVLNSLHFRLSVPTTKTFLRRFI---------- 321

  Fly   485 SFSQIGRQKSAEADD--AFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSY-----SVLAAAAISH 542
                    ::|:|.|  ..|..::....|.:.:           :..|::     |::||:|:
plant   322 --------RAAQASDKVPLIEMEYLANYFAELT-----------LTEYTFLRFLPSLIAASAV-- 365

  Fly   543 TFSREMALRCSGLDW-QVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTD 606
             |.....|..|...| |.:|...|:.....:........||||                    |.
plant   366 -FLARWTLDQSNHPWNQTLQHYTRYETSALKNTVLAMEELQLN--------------------TS 409

  Fly   607 DSHIIQTHT 615
            .|.:|..||
plant   410 GSTLIAIHT 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	48/129 (37%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044	12/59 (20%)
CYCA2;1	NP_001332473.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920