DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycE and CYCB2;2

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_195287.1	Gene:	CYCB2;2 / 829714	AraportID:	AT4G35620	Length:	429	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	119/523 - (22%)
Similarity:	193/523 - (36%)	Gaps:	142/523 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 LSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSSP 180
            |..|.....:.|.|   .|||.|  ...|....||  |.:..|...|....|.|.::..|.....
plant    20 LQDDDKRSRKFGVE---MKRQNR--RALGVINHNL--VGAKAYPCVVNKRRGLSQRKQESCDKKK 77

  Fly   181 AEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVV---------------VRYAAEQVVTSTVVTQKT 230
            .:.|.              ||..|..::|..:               .....|:|.....:....
plant    78 LDSLH--------------PSISRSQEETKKLKPSGNEFGDCIFIDEEEEKNEEVTLDQPMPMSL 128

  Fly   231 EDDDLLDDSCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQI 295
            |:..:..|..|:....||.|::.||...|::.|.:..|.|:                       :
plant   129 EEPYIEFDPMEEEVEMEDMEEEQEEPVLDIDEYDANNSLAA-----------------------V 170

  Fly   296 HHPVSDLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGL 360
            .: |.||.                             |.:|    :.|:.|.: .:..:.|...:
plant   171 EY-VQDLY-----------------------------DFYR----KTERFSCV-PLDYMAQQFDI 200

  Fly   361 QPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEI 425
            ..:|||||:||||||.:.::|..||.:|.|:.:||:|. ...|.:..|||:|:..|.:|.|.||:
plant   201 SDKMRAILIDWLIEVHDKFELMNETLFLTVNLIDRFLS-KQAVARKKLQLVGLVALLLACKYEEV 264

  Fly   426 YPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIG 490
            ..|.:.:...::|.|.|..|:|..|||:|..|.:::|                   .|..:..:.
plant   265 SVPIVEDLVVISDKAYTRTDVLEMEKIMLSTLQFNMS-------------------LPTQYPFLK 310

  Fly   491 R-QKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAI------SHTFSR-- 546
            | .|:|::|...         .:..|.|::|..:|..|..|..|:|||.|:      .|.||.
plant   311 RFLKAAQSDKKL---------EILASFLIELALVDYEMVRYPPSLLAATAVYTAQCTIHGFSEWN 366

  Fly   547 -EMALRCSGLDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNEQV-SNKFG---LGLICPNIVTD 606
             .....|...:.|:::.|.|.:.     :.|||...:|...:.:. |:|||   ......:.:..
plant   367 STCEFHCHYSENQLLECCRRMVR-----LHQKAGTDKLTGVHRKYSSSKFGYIATKYEAAHFLVS 426

  Fly   607 DSH 609
            |||
plant   427 DSH 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	45/128 (35%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044	17/62 (27%)
CYCB2;2	NP_195287.1	COG5024	<157..412	CDD:227357	82/346 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920