Protein Alignment CycE and CCND1

DIOPT Version :9

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_444284.1
• Gene: CCND1 / 595
• HGNCID: 1582
• Length: 295
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 70/305 - (22%)
• Similarity: 120/305 - (39%)
• Gaps: 83/305 - (27%)

  Fly   362 PRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIY 426
            |.||.|:..|::||||..|...|.|.||::||||:|.: ..|:|:.|||:|.||:|||:|::|..
Human    54 PSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSL-EPVKKSRLQLLGATCMFVASKMKETI 117

  Fly   427 PPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQ--I 489
            |....:....||.:....::|..|.:|:..|.|:::.:                 ||..|.:  :
Human   118 PLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAM-----------------TPHDFIEHFL 165

  Fly   490 GRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCSG 554
            .:...||.:...|......|        :.||..||...:...|::||.::
Human   166 SKMPEAEENKQIIRKHAQTF--------VALCATDVKFISNPPSMVAAGSV-------------- 208

  Fly   555 LDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMD 619
                                               |:...||.|..||      :.:..:..|..
Human   209 -----------------------------------VAAVQGLNLRSPN------NFLSYYRLTRF 232

  Fly   620 MYDEVLMAQDAAHAMRARIQASPATALRAPESLLTPPASSHKPDE 664
            :...:....|...|.:.:|:|...::||..:..:.|.|:..:.:|
Human   233 LSRVIKCDPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEE 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	40/99 (40%)
		Cyclin_C	<517..>571	CDD:281044	7/53 (13%)
CCND1	NP_444284.1	CYCLIN_CCND1_rpt1	3..151	CDD:410276	39/97 (40%)
		CYCLIN_CCND1_rpt2	156..265	CDD:410279	27/171 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..295		3/16 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146269
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840