Protein Alignment CycE and Ccnd1

DIOPT Version :10

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_008758390.1
• Gene: Ccnd1 / 58919
• RGDID: 68384
• Length: 317
• Species: Rattus norvegicus
• Alignment Length: 351
• Identity: 81/351 - (23%)
• Similarity: 131/351 - (37%)
• Gaps: 122/351 - (34%)

  Fly   362 PRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIY 426
            |.||.|:..|::||||..|...|.|.||::||||:|.: ..::|:.|||:|.||:|||:|::|..
  Rat    54 PSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSL-EPLKKSRLQLLGATCMFVASKMKETI 117

  Fly   427 PPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGR 491
            |....:....||.:....::|..|.:|:..|.|:::.:                 ||..|.:...
  Rat   118 PLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAM-----------------TPHDFIEHFL 165

  Fly   492 QKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAI---------------- 540
            .|..|||:.....:.....||.      ||..||...:...|::||.::
  Rat   166 SKMPEADENKQIIRKHAQTFVA------LCATDVKFISNPPSMVAAGSVVAAMQGLNLGSPNNFL 224

  Fly   541 -----SHTFSREMALRC-------SGLDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNK 593
                 :|..||  .::|       :||          |:                        ||
  Rat   225 SCYRTTHFLSR--VIKCDPVKALATGL----------WL------------------------NK 253

  Fly   594 FGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMAQDAAHAMRARIQASPATALRAPESLLTPPAS 658
            ..|.|..|                         .||...|.:.:|:|...::||..:..:.|.|:
  Rat   254 DSLHLRPP-------------------------LQDCLRACQEQIEALLESSLRQAQQNIDPKAT 293

  Fly   659 SHKPDEYLGDEGDETGARSGISSTTT 684
                     :|..|....:|::.|.|
  Rat   294 ---------EEEGEVEEEAGLACTPT 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	CYCLIN_CCNE_rpt1	327..459	CDD:410223	38/96 (40%)
		CYCLIN_CCNE_rpt2	463..576	CDD:410224	23/140 (16%)
Ccnd1	XP_008758390.1	CYCLIN_CCND1_rpt1	3..151	CDD:410276	38/97 (39%)
		CYCLIN_CCND1_rpt2	156..287	CDD:410279	35/197 (18%)