Protein Alignment CycE and Ccne2

DIOPT Version :9

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001102126.1
• Gene: Ccne2 / 362485
• RGDID: 1307783
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 166/489 - (33%)
• Similarity: 248/489 - (50%)
• Gaps: 88/489 - (17%)

  Fly   174 LSIRSSPAEDLSEAPHSPLPDSPDSPPSPDRGSKQTPVVVRYAAEQVVTSTVVTQKTEDDDLLDD 238
            :|.|||..:  ::..|: .|:.||||        |...:::  |::..|:..|.::||      :
  Rat     1 MSRRSSRLQ--AKQQHA-RPNQPDSP--------QEAQIIQ--AKKRKTAQDVKKRTE------E 46

  Fly   239 SCEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVSDLM 303
            ..:.:.|        |..:....:.|..|||    |...:..:.|  .|........::...:|.
  Rat    47 ITKKHQY--------EIRNCWPPVLSGGISP----CIIIETPHKE--IGTSDFSRFTNYRFKNLF 97

  Fly   304 INMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAIL 368
            ||      |:        |||.|:||.:.:||:.|..::.:....:...:|  |..|:|:||:||
  Rat    98 IN------PS--------PLPDLSWACSQEVWQNMLQKESRYVHDKHFEVL--HSDLEPQMRSIL 146

  Fly   369 LDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEF 433
            ||||:||||||.|||||||||.|:.||::.....|.|..|||||||.||:|:|:||||.||:.||
  Rat   147 LDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDVNKNMLQLIGITSLFIASKLEEIYAPKLQEF 211

  Fly   434 AYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGRQKSAEAD 498
            ||||||||:|.|||..|..:|:||.|::.|:|:..||.:::|::.....|
  Rat   212 AYVTDGACSEVDILKMELNILKALKWELCPVTVISWLNLFLQVDAVKDIP--------------- 261

  Fly   499 DAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCSGLDWQVIQPC 563
             ..:.||:|...|:|.:||||||.|.:....:.|.:|||||:.|..|.|:..:.|||:|..|..|
  Rat   262 -KVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILAAAALCHFTSIEVVKKASGLEWDDISEC 325

  Fly   564 ARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMAQ 628
            ..||.||..|:...:| ::|....:              |..:|.|.|||||..:.:.:||
  Rat   326 VDWMVPFVSVVKSVSP-VKLKTFKK--------------IPMEDRHNIQTHTNYLALLNEV---- 371

  Fly   629 DAAHAMRARIQASPATALRAPESLLTPPASSHKP 662
            :..:..|...|.||.    ....::|||.|:.||
  Rat   372 NYVNIFRKGGQLSPV----CNGGIMTPPKSTEKP 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	71/128 (55%)
		Cyclin_C	<517..>571	CDD:281044	24/53 (45%)
Ccne2	NP_001102126.1	CYCLIN_SF	101..237	CDD:424085	76/145 (52%)
		CYCLIN_SF	241..329	CDD:424085	33/103 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339984
Domainoid	1	1.000	156	1.000	Domainoid score	I4095
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	271	1.000	Inparanoid score	I2923
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0002994
OrthoInspector	1	1.000	-	-		otm45307
orthoMCL	1	0.900	-	-		OOG6_105145
Panther	1	1.100	-	-	O	PTHR10177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2342
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.760