Protein Alignment CycE and Ccnb1

DIOPT Version :9

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_758505.2
• Gene: Ccnb1 / 268697
• MGIID: 88302
• Length: 430
• Species: Mus musculus
• Alignment Length: 441
• Identity: 106/441 - (24%)
• Similarity: 166/441 - (37%)
• Gaps: 131/441 - (29%)

  Fly   103 TAATSNGNKRKRRLSSDSNE-DPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVD 166
            |||:..|.:.:..|....|: ..||....|..:..:.|    |:.:|.:.::...|...||.
Mouse    32 TAASKPGLRPRTALGDIGNKVSEELQARVPLKREAKTL----GTGKGTVKALPKPVEKVPVC--- 89

  Fly   167 GQSTQELLSIRSSP-AEDLSEAPHSPLPDSPDSP-PSPDRGSKQTPVVVRYAAEQVVTSTVVTQK 229
             :...||......| .|.:.|...||.|...|:| |||...|...| ...|..:......:....
Mouse    90 -EPEVELAEPEPEPELEHVREEKLSPEPILVDNPSPSPMETSGCAP-AEEYLCQAFSDVILAVSD 152

  Fly   230 TEDDDLLDDS-CEDYSYDEDDEDDVEEEDDDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQE 293
            .:.||..|.: |.:|..|               ||:.
Mouse   153 VDADDGADPNLCSEYVKD---------------IYAY---------------------------- 174

  Fly   294 QIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHP 358
                                    |||.                   .:||..|.:.:...|
Mouse   175 ------------------------LRQL-------------------EEEQSVRPKYLQGRE--- 193

  Fly   359 GLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHLQLIGITCLFVAAKVE 423
             :...|||||:||||:|...::|.:||.|:.|..:||::..: .|.|..|||:|:|.:|:|:|.|
Mouse   194 -VTGNMRAILIDWLIQVQMKFRLLQETMYMTVSIIDRFMQNS-CVPKKMLQLVGVTAMFIASKYE 256

  Fly   424 EIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQ 488
            |:|||:||:||:||:...|:..|...|..:|:.|::.         ||..:.|:...|.    |:
Mouse   257 EMYPPEIGDFAFVTNNTYTKHQIRQMEMKILRVLNFS---------LGRPLPLHFLRRA----SK 308

  Fly   489 IGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAA 539
            :|     |.|..         :......|::|..||..|.:::.|.:||.|
Mouse   309 VG-----EVDVE---------QHTLAKYLMELSMLDYDMVHFAPSQIAAGA 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	47/128 (37%)
		Cyclin_C	<517..>571	CDD:281044	9/23 (39%)
Ccnb1	NP_758505.2	Interaction with CDK2. /evidence=ECO:0000250	166..174		4/22 (18%)
		Cyclin_N	170..295	CDD:278560	53/224 (24%)
		Interaction with CDK2. /evidence=ECO:0000250	255..258		1/2 (50%)
		Cyclin_C	297..415	CDD:281044	15/67 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750