Protein Alignment CycE and cye-1

DIOPT Version :10

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001021027.1
• Gene: cye-1 / 172399
• WormBaseID: WBGene00000871
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 153/600 - (25%)
• Similarity: 253/600 - (42%)
• Gaps: 123/600 - (20%)

  Fly    72 SQRSEEELPGTSAASRTDEMCS----------------------CDSQNLAASTAATSNGNKRKR 114
            |.|:.|.:|.|....|...:.|                      .:::|.:..:..:.....|||
 Worm     6 SSRTAERVPTTQKPERKSAILSPHDELRERLLETAIDMKENIPQRNTRNSSVGSQKSDCSETRKR 70

  Fly   115 RLSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSS 179
            |.:.          |.|:|||........||.:.:|..::.......|.|...||
 Worm    71 RSTK----------EGPAAKRHSGEKHRNGSREDSLEYISEYSDDREVGSSSSQS---------- 115

  Fly   180 PAEDLSEAPHSPLPDSPDSPPSPDRG--------SKQTPVVVRYAAEQVVTSTVVTQKTEDDDLL 236
                 |.....|||..|:.....|:.        |:::..:||....|     .:.::.|||  .
 Worm   116 -----SRTRGQPLPAMPEEEEVFDKSSSSDNLAESEESHEMVRLEERQ-----DIEEEIEDD--F 168

  Fly   237 DDSCEDYSYDEDDEDDVEEED-DDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVS 300
            ||..||...|:::.:::|.|| ||..:.:...:..      ::.:|.|.
 Worm   169 DDEEEDVVNDKEEYEEIESEDEDDYPVQNEGFAVT------KRLMNDEH---------------- 211

  Fly   301 DLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMR 365
              |:...|.:|.|..:|:          .:...||.||..|||.....|  .:|..||.:....|
 Worm   212 --MVTAPTFLSTAKCDGI----------GSPTKVWSLMVKRDEIPRATR--FLLGNHPDMDDEKR 262

  Fly   366 AILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAH-KVQKTHLQLIGITCLFVAAKVEEIYPPK 429
            .||:||::||||..|||||||:|||||:||||..:: :....:.||:|...||:|||.|||||||
 Worm   263 RILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKYEEIYPPK 327

  Fly   430 IGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGRQKS 494
            ..:||::||.|.|..:|...|.::::.:.|.:.|||...||..|:||....:         :.||
 Worm   328 CIDFAHLTDSAFTCDNIRTMEVLIVKYIGWSLGPITSIQWLSTYLQLLGTGK---------KNKS 383

  Fly   495 AEADDAFIY-PQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMAL-RCSGLDW 557
            ...::..:| |:....|:::..::||....::....:||..:|||.:...:....|: :.:|...
 Worm   384 DHYEEQNMYVPELLRSEYLEMCKILDFLLFEIDSFTFSYRTIAAAVLFVNYEPTCAVEKATGFMQ 448

  Fly   558 QVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYD 622
            ..::....::||..|..:::...|      :.|..|.      .:|.:||||.||.:.....|..
 Worm   449 AQLEKVIEYVEPVCRAFAKQRQLL------DDVIPKH------ESIKSDDSHNIQVYVKRSSMEP 501

  Fly   623 EVLMAQDAAHAMRAR 637
            .|...::....::||
 Worm   502 IVKSERERIQHLKAR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	CYCLIN_CCNE_rpt1	327..459	CDD:410223	59/132 (45%)
		CYCLIN_CCNE_rpt2	463..576	CDD:410224	25/114 (22%)
cye-1	NP_001021027.1	CYCLIN_CCNE_rpt1	226..357	CDD:410223	60/142 (42%)
		CYCLIN_CCNE_rpt2	361..463	CDD:410224	24/110 (22%)