Protein Alignment CycE and cye-1

DIOPT Version :9

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001021027.1
• Gene: cye-1 / 172399
• WormBaseID: WBGene00000871
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 153/600 - (25%)
• Similarity: 253/600 - (42%)
• Gaps: 123/600 - (20%)

  Fly    72 SQRSEEELPGTSAASRTDEMCS----------------------CDSQNLAASTAATSNGNKRKR 114
            |.|:.|.:|.|....|...:.|                      .:::|.:..:..:.....|||
 Worm     6 SSRTAERVPTTQKPERKSAILSPHDELRERLLETAIDMKENIPQRNTRNSSVGSQKSDCSETRKR 70

  Fly   115 RLSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQELLSIRSS 179
            |.:.          |.|:|||........||.:.:|..::.......|.|...||
 Worm    71 RSTK----------EGPAAKRHSGEKHRNGSREDSLEYISEYSDDREVGSSSSQS---------- 115

  Fly   180 PAEDLSEAPHSPLPDSPDSPPSPDRG--------SKQTPVVVRYAAEQVVTSTVVTQKTEDDDLL 236
                 |.....|||..|:.....|:.        |:::..:||....|     .:.::.|||  .
 Worm   116 -----SRTRGQPLPAMPEEEEVFDKSSSSDNLAESEESHEMVRLEERQ-----DIEEEIEDD--F 168

  Fly   237 DDSCEDYSYDEDDEDDVEEED-DDVEIYSSTISPASSGCSQQQAVNGERTPGLPKHQEQIHHPVS 300
            ||..||...|:::.:::|.|| ||..:.:...:..      ::.:|.|.
 Worm   169 DDEEEDVVNDKEEYEEIESEDEDDYPVQNEGFAVT------KRLMNDEH---------------- 211

  Fly   301 DLMINMRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMR 365
              |:...|.:|.|..:|:          .:...||.||..|||.....|  .:|..||.:....|
 Worm   212 --MVTAPTFLSTAKCDGI----------GSPTKVWSLMVKRDEIPRATR--FLLGNHPDMDDEKR 262

  Fly   366 AILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAH-KVQKTHLQLIGITCLFVAAKVEEIYPPK 429
            .||:||::||||..|||||||:|||||:||||..:: :....:.||:|...||:|||.|||||||
 Worm   263 RILIDWMMEVCESEKLHRETFHLAVDYVDRYLESSNVECSTDNFQLVGTAALFIAAKYEEIYPPK 327

  Fly   430 IGEFAYVTDGACTERDILNHEKILLQALDWDISPITITGWLGVYMQLNVNNRTPASFSQIGRQKS 494
            ..:||::||.|.|..:|...|.::::.:.|.:.|||...||..|:||....:         :.||
 Worm   328 CIDFAHLTDSAFTCDNIRTMEVLIVKYIGWSLGPITSIQWLSTYLQLLGTGK---------KNKS 383

  Fly   495 AEADDAFIY-PQFSGFEFVQTSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMAL-RCSGLDW 557
            ...::..:| |:....|:::..::||....::....:||..:|||.:...:....|: :.:|...
 Worm   384 DHYEEQNMYVPELLRSEYLEMCKILDFLLFEIDSFTFSYRTIAAAVLFVNYEPTCAVEKATGFMQ 448

  Fly   558 QVIQPCARWMEPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYD 622
            ..::....::||..|..:::...|      :.|..|.      .:|.:||||.||.:.....|..
 Worm   449 AQLEKVIEYVEPVCRAFAKQRQLL------DDVIPKH------ESIKSDDSHNIQVYVKRSSMEP 501

  Fly   623 EVLMAQDAAHAMRAR 637
            .|...::....::||
 Worm   502 IVKSERERIQHLKAR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	60/129 (47%)
		Cyclin_C	<517..>571	CDD:281044	11/54 (20%)
cye-1	NP_001021027.1	Cyclin_N	233..360	CDD:278560	60/128 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167674
Domainoid	1	1.000	112	1.000	Domainoid score	I3894
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I2779
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	1	1.000	-	-		FOG0002994
OrthoInspector	1	1.000	-	-		oto20039
orthoMCL	1	0.900	-	-		OOG6_105145
Panther	1	1.100	-	-	LDO	PTHR10177
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2444
SonicParanoid	1	1.000	-	-		X2342
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.930