Protein Alignment CycE and Ccna2

DIOPT Version :9

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_008759125.1
• Gene: Ccna2 / 114494
• RGDID: 621059
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 128/589 - (21%)
• Similarity: 213/589 - (36%)
• Gaps: 192/589 - (32%)

  Fly   109 GNKRK--RRLSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQ 171
            ||.|:  ..|.|...:...:..|..:..:|.|..|:..:.:                 |.|.:.|
  Rat     3 GNSRQAGSALLSQQEDQENVNPEKVAPAQQPRAQAVLKAGK-----------------VRGPAPQ 50

  Fly   172 ELLSIRS-SPAEDLSEAPHSPLPDS-PDSPPSPDRGSKQTPVVVRY-AAEQVVTSTVVTQKTEDD 233
            :.|..|. :|.:||      |:.|. ..:.||....|||....:.. .||:........::|:.:
  Rat    51 QRLKTRRVAPLKDL------PINDEHVPTVPSWKAVSKQPAFTIHVDEAEETQKRPAEQKETQCE 109

  Fly   234 DLLDDSCE-------------DYSYDEDDED----------------DVEEEDDDVEIYSSTISP 269
            |.|..|..             ||..|.....                |:..|..|||      ||
  Rat   110 DALAFSAAVSLPGARKPLVPLDYPMDGSFGQTHGRQNSCYRQLCRCYDLTVETRDVE------SP 168

  Fly   270 ASSGCS----QQQAVNGERTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWAN 330
            .:...|    .::.||...   :|.:.|.||..:.::.:..:.
  Rat   169 HAMDISIVLEDEKPVNVNE---VPDYHEDIHTYLREMEVKCKP---------------------- 208

  Fly   331 AADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDR 395
                               .:|.:::.|.:...|||||:|||:||.|.|||..||.:|||:|:||
  Rat   209 -------------------KVSYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDR 254

  Fly   396 YLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWD 460
            :|. :..|.:..|||:|...:.:|:|.||||||::.||.|:||...:::.:|..|.::|:.|.:|
  Rat   255 FLS-SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFD 318

  Fly   461 ISPITITGWLGVY-MQLNVNNRTPASFSQ-IGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTL 523
            ::..|:..:|..| :.|...|....|.:. :|.....:||....|                |.:|
  Rat   319 LAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKY----------------LPSL 367

  Fly   524 DVGMANYSYSVLAAAAISHTFSREMALRCSGLDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNE 588
            ..|.|.:    ||...::.....|..::.:|...:.::||
  Rat   368 IAGAAFH----LALYTVTGQSWPESLVQKTGYTLESLKPC------------------------- 403

  Fly   589 QVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMA-QDAAHAMRARIQASPATALRAPESL 652
                                        .||::...|.| |.|..::|.:.:.|...::    ||
  Rat   404 ----------------------------LMDLHQTYLKAPQHAQQSIREKYKHSKYHSV----SL 436

  Fly   653 LTPP 656
            |.||
  Rat   437 LNPP 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	48/128 (38%)
		Cyclin_C	<517..>571	CDD:281044	10/53 (19%)
Ccna2	XP_008759125.1	Cyclin_N2	17..174	CDD:293109	35/185 (19%)
		Cyclin_N	194..320	CDD:278560	50/167 (30%)
		Cyclin_C	322..440	CDD:281044	31/194 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750