Protein Alignment CycE and Ccna2

DIOPT Version :10

• Sequence 1: NP_001246037.1
• Gene: CycE / 34924
• FlyBaseID: FBgn0010382
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_008759125.1
• Gene: Ccna2 / 114494
• RGDID: 621059
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 128/589 - (21%)
• Similarity: 213/589 - (36%)
• Gaps: 192/589 - (32%)

  Fly   109 GNKRK--RRLSSDSNEDPELGFEPPSAKRQQRLPALYGSEQGNLSSVASSVYTSPVVSVDGQSTQ 171
            ||.|:  ..|.|...:...:..|..:..:|.|..|:..:.:                 |.|.:.|
  Rat     3 GNSRQAGSALLSQQEDQENVNPEKVAPAQQPRAQAVLKAGK-----------------VRGPAPQ 50

  Fly   172 ELLSIRS-SPAEDLSEAPHSPLPDS-PDSPPSPDRGSKQTPVVVRY-AAEQVVTSTVVTQKTEDD 233
            :.|..|. :|.:||      |:.|. ..:.||....|||....:.. .||:........::|:.:
  Rat    51 QRLKTRRVAPLKDL------PINDEHVPTVPSWKAVSKQPAFTIHVDEAEETQKRPAEQKETQCE 109

  Fly   234 DLLDDSCE-------------DYSYDEDDED----------------DVEEEDDDVEIYSSTISP 269
            |.|..|..             ||..|.....                |:..|..|||      ||
  Rat   110 DALAFSAAVSLPGARKPLVPLDYPMDGSFGQTHGRQNSCYRQLCRCYDLTVETRDVE------SP 168

  Fly   270 ASSGCS----QQQAVNGERTPGLPKHQEQIHHPVSDLMINMRTPMSPAVENGLRQCPLPALAWAN 330
            .:...|    .::.||...   :|.:.|.||..:.::.:..:.
  Rat   169 HAMDISIVLEDEKPVNVNE---VPDYHEDIHTYLREMEVKCKP---------------------- 208

  Fly   331 AADVWRLMCHRDEQDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDR 395
                               .:|.:::.|.:...|||||:|||:||.|.|||..||.:|||:|:||
  Rat   209 -------------------KVSYMKRQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDR 254

  Fly   396 YLHVAHKVQKTHLQLIGITCLFVAAKVEEIYPPKIGEFAYVTDGACTERDILNHEKILLQALDWD 460
            :|. :..|.:..|||:|...:.:|:|.||||||::.||.|:||...:::.:|..|.::|:.|.:|
  Rat   255 FLS-SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYSKKQVLRMEHLVLKVLAFD 318

  Fly   461 ISPITITGWLGVY-MQLNVNNRTPASFSQ-IGRQKSAEADDAFIYPQFSGFEFVQTSQLLDLCTL 523
            ::..|:..:|..| :.|...|....|.:. :|.....:||....|                |.:|
  Rat   319 LAAPTVNQFLTQYFLHLQPANCKVESLAMFLGELSLIDADPYLKY----------------LPSL 367

  Fly   524 DVGMANYSYSVLAAAAISHTFSREMALRCSGLDWQVIQPCARWMEPFFRVISQKAPYLQLNEQNE 588
            ..|.|.:    ||...::.....|..::.:|...:.::||
  Rat   368 IAGAAFH----LALYTVTGQSWPESLVQKTGYTLESLKPC------------------------- 403

  Fly   589 QVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMA-QDAAHAMRARIQASPATALRAPESL 652
                                        .||::...|.| |.|..::|.:.:.|...::    ||
  Rat   404 ----------------------------LMDLHQTYLKAPQHAQQSIREKYKHSKYHSV----SL 436

  Fly   653 LTPP 656
            |.||
  Rat   437 LNPP 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	CYCLIN_CCNE_rpt1	327..459	CDD:410223	47/131 (36%)
		CYCLIN_CCNE_rpt2	463..576	CDD:410224	20/114 (18%)
Ccna2	XP_008759125.1	Cyclin_N2	85..174	CDD:465146	16/94 (17%)
		CYCLIN_CCNA2_rpt1	188..318	CDD:410264	51/171 (30%)
		CYCLIN_CCNA2_rpt2	322..432	CDD:410267	28/182 (15%)