DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CycE and ccni2

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	XP_003200952.1	Gene:	ccni2 / 100330479	ZFINID:	ZDB-GENE-081106-2	Length:	310	Species:	Danio rerio

Alignment Length:	201	Identity:	46/201 - (22%)
Similarity:	81/201 - (40%)	Gaps:	57/201 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   284 RTPGLPKHQEQIHHPVSDLMIN-----MRTPMSPAVENGLRQCPLPALAWANAADVWRLMCHRDE 343
            :.||     |:.:..:..|::|     ||...:|.::||..|          .:|
Zfish     2 KLPG-----EEENQRLGTLLLNTLDREMRLWRAPVLKNGCIQ----------GSD---------- 41

  Fly   344 QDSRLRSISMLEQHPGLQPRMRAILLDWLIEVCEVYKLHRETFYLAVDYLDRYLHVAHKVQKTHL 408
                   ||..:.|        .::| ||.|:..:::...||..|.|..|:..|... |.|..:|
Zfish    42 -------ISPSQYH--------EVIL-WLREMNVIFQFSTETLALGVCVLNSLLATV-KTQLKYL 89

  Fly   409 QLIGITCLFVAAKVEEIYPPKIGEFAYVTD----GAC--TERDILNHEKILLQALDWDISPITIT 467
            :.:.||.|.:|||:.|    :....|.|.|    ..|  :..:||..|:::|..|.|::...|..
Zfish    90 KCMAITSLILAAKINE----EDEVIASVKDLLEQSRCKFSTAEILRMERVILHKLHWELYLATPM 150

  Fly   468 GWLGVY 473
            .::.::
Zfish   151 DFIHIF 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	34/134 (25%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044
ccni2	XP_003200952.1	Cyclin_N	36..144	CDD:278560	35/148 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740