DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CycE and ccnjl

DIOPT Version :9

Sequence 1:	NP_001246037.1	Gene:	CycE / 34924	FlyBaseID:	FBgn0010382	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001296774.1	Gene:	ccnjl / 100001904	ZFINID:	ZDB-GENE-030131-9888	Length:	407	Species:	Danio rerio

Alignment Length:	368	Identity:	73/368 - (19%)
Similarity:	131/368 - (35%)	Gaps:	105/368 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 WRLMCHRD-EQDSRLRSISMLEQHPGLQPR--MRAILLDWLIEVCEVYKLHRETFYLAVDYLDRY 396
            |:.....| .|..|::.:. |..:....|:  ||....|.|..:...|:|.....:|||..||.:
Zfish    11 WKTQLAADIHQALRIKELK-LPTYQAHSPQIGMRRYFADLLAVLSNRYQLCPTARHLAVYLLDLF 74

  Fly   397 L-HVAHKVQKTHLQLIGITCLFVAAKVEEIYP--PKIGE-----FAYVTDGACTERDILNHEKIL 453
            : |  :.|....|.:|.::||.:|:|.||...  ||:.:     |....:....:||::..|.:|
Zfish    75 MDH--YDVAVRQLYVIALSCLLLASKFEEKEDRVPKLEQLNTLGFMCSLNLTLNKRDLIKMELLL 137

  Fly   454 LQALDWDISPITITGWLGVYMQL-----NVNNRTPASFSQIGRQKSAEADDAFIYPQFSGFEFVQ 513
            |:...|::...|...::..|:..     :::|..|  .|.:.:.|:              |....
Zfish   138 LETFGWNLCMPTPAHFIDYYLHAAVQEGDLHNGWP--LSSLSKTKA--------------FMDKY 186

  Fly   514 TSQLLDLCTLDVGMANYSYSVLAAAAISHTFSREMALRCS-----------GLDWQVIQPCARWM 567
            |...|::...|....::..|.:|||.|:   :..:.|:.|           |..|..:..|.:.|
Zfish   187 THYFLEVSLQDHAFLSFRPSQVAAACIA---ASRICLQISPSWTTVLHLLTGYSWDHLTQCIQLM 248

  Fly   568 EPFFRVISQKAPYLQLNEQNEQVSNKFGLGLICPNIVTDDSHIIQTHTTTMDMYDEVLMAQDAAH 632
                         |..::.:.:.:||                              ...:..|..
Zfish   249 -------------LLAHDNDVKEANK------------------------------SKSSPSAGQ 270

  Fly   633 AMRARIQASPATAL----RAPES-----LLT----PPASSHKP 662
            :::.:....|:||.    |.|.|     ||.    |..|.|.|
Zfish   271 SLQPQAHVPPSTAAPSLHRQPTSSSQQLLLQASSYPQLSQHSP 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CycE	NP_001246037.1	Cyclin_N	333..462	CDD:278560	36/137 (26%)
CycE	NP_001246037.1	Cyclin_C	<517..>571	CDD:281044	13/64 (20%)
ccnjl	NP_001296774.1	Cyclin_N	18..146	CDD:278560	35/130 (27%)
		Cyclin_C	148..>254	CDD:281044	22/137 (16%)
		STAT6_C	255..>344	CDD:291272	15/89 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579808
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D993640at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850