DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18478 and prss60.1

DIOPT Version :9

Sequence 1:	NP_609764.1	Gene:	CG18478 / 34923	FlyBaseID:	FBgn0028517	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	243	Identity:	74/243 - (30%)
Similarity:	110/243 - (45%)	Gaps:	24/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 FPWTIAVIHNRSLVG---GGSLITPDIVLTAAHRIFNKDVEDIVVSAGEWEYGSALEKYPFEEAF 116
            :||.:: :|:....|   |||||..:.||||||.:.......::|..|:... ..:..|.....
Zfish    45 WPWQVS-LHSPIYGGHFCGGSLINSEWVLTAAHCLPRITTSSLLVFLGKTTQ-QGVNTYEINRT- 106

  Fly   117 VLKMVIHKSFNYQRGANNLALLFLDREFPLTYKINTICLPTQKRSL-SSTRCIVAGWGKYQFS-D 179
            |..:.:|.|:|.....|::|||.|......:..|..:||..|.... :.|...:.|||..|.. :
Zfish   107 VSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVN 171

  Fly   180 THYGGVLKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAG-GEKDNDACTGDGGGALFCPMT 243
            ....|:|::..:|:||...|...|....:..|      :|||| .:...|.|.||.||    ||.
Zfish   172 LPAPGILQETMIPVVPNDQCNALLGSGSVTNN------MICAGLLQGGRDTCQGDSGG----PMV 226

  Fly   244 EDPKQ---FEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQQIKENL 288
            .  ||   :.|.||.:||.||.:...|..||.|.:::.||...|.:||
Zfish   227 S--KQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSWINSIIVQNL 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..283	CDD:238113	71/236 (30%)
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	69/233 (30%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	69/233 (30%)
		Tryp_SPc	34..267	CDD:238113	71/236 (30%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840