DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18478 and Prss21

DIOPT Version :9

Sequence 1:	NP_609764.1	Gene:	CG18478 / 34923	FlyBaseID:	FBgn0028517	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_065233.2	Gene:	Prss21 / 57256	MGIID:	1916698	Length:	324	Species:	Mus musculus

Alignment Length:	317	Identity:	91/317 - (28%)
Similarity:	136/317 - (42%)	Gaps:	49/317 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TLIVALFVLGVAENVENLQ----QIEELKCGYGNPDAVK-------VQFNVTEG-QAKPAEFPW- 57
            ||:..|.|:..|...  ||    |::..|.....||.:.       :...:..| .|:...:||
Mouse     7 TLVPLLVVVATAAMA--LQSTYLQVDPEKPELQEPDLLSGPCGHRTIPSRIVGGDDAELGRWPWQ 69

  Fly    58 -TIAVIHNRSLVGGGSLITPDIVLTAAHRIFNKDVE--DIVVSAGE-------WEYGSALEKYPF 112
             ::.|..|.  :.|.:|:....|||||| .|.||.:  |..|..||       |...:...:|..
Mouse    70 GSLRVWGNH--LCGATLLNRRWVLTAAH-CFQKDNDPFDWTVQFGELTSRPSLWNLQAYSNRYQI 131

  Fly   113 EEAFVLKMVIHKSFNY-QRGANNLALLFLDREFPLTYK--INTICLPTQKRSLSS-TRCIVAGWG 173
            |:.|:       |..| ::..|::|||.|..  |:||.  |..|||........: |.|.|.|||
Mouse   132 EDIFL-------SPKYSEQYPNDIALLKLSS--PVTYNNFIQPICLLNSTYKFENRTDCWVTGWG 187

  Fly   174 KY-QFSDTHYGGVLKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAG-GEKDNDACTGDGGG 236
            .. :.........|:::.:.|:...:|....:|.....|  :...::||| .|...|||.||.||
Mouse   188 AIGEDESLPSPNTLQEVQVAIINNSMCNHMYKKPDFRTN--IWGDMVCAGTPEGGKDACFGDSGG 250

  Fly   237 ALFCPMTEDPKQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQ-QIKENLYTPD 292
            .|.|   :....:.|:|:|:||:||...|.|..||::.....||.. .|:..|..||
Mouse   251 PLAC---DQDTVWYQVGVVSWGIGCGRPNRPGVYTNISHHYNWIQSTMIRNGLLRPD 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..283	CDD:238113	75/250 (30%)
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	73/246 (30%)
Prss21	NP_065233.2	Tryp_SPc	54..291	CDD:214473	74/253 (29%)
Prss21	NP_065233.2	Tryp_SPc	55..294	CDD:238113	76/255 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8716
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910