DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18478 and prss60.2

DIOPT Version :9

Sequence 1:	NP_609764.1	Gene:	CG18478 / 34923	FlyBaseID:	FBgn0028517	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	269	Identity:	83/269 - (30%)
Similarity:	120/269 - (44%)	Gaps:	48/269 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 NVTEGQAKPAEFPWTIAVIHNRSLVG----GGSLITPDIVLTAAHRIFNKDVEDIVVSAG-EWEY 103
            |..||     .:||.:::...|  .|    |||||:.:.||||||.:.......:||..| ..:.
Zfish    39 NAPEG-----SWPWQVSLQSPR--YGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGRRTQQ 96

  Fly   104 GSALEKYPFEEAFVLKMVIHKSFNYQRGANNLALLFLDREFPLTYKINTICLPTQKRSLSS-TRC 167
            |....:   ....|.|:::|.|:|.....|::|||.|.........|..:||..|....|: |..
Zfish    97 GVNTHE---TSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQNSVYSAGTSS 158

  Fly   168 IVAGWGKYQFSDTHYG------GVLKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAGGEK- 225
            .:.|||     |...|      |:|::..:|:|....|..|     ||.. |:...:||||..|
Zfish   159 WITGWG-----DVQAGVNLPAPGILQETMIPVVANDRCNAQ-----LGSG-TVTNNMICAGLAKG 212

  Fly   226 DNDACTGDGGGAL---FCPMTEDPKQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQQIKEN 287
            ..|.|.||.||.:   .|.:      :.|.||.:||.||.:.|.|..||.|.:::.||..:|.:|
Zfish   213 GKDTCQGDSGGPMVTRLCTV------WIQAGITSWGYGCADPNSPGVYTRVSQYQSWISSKISQN 271

  Fly   288 -----LYTP 291
                 |:||
Zfish   272 QPGFILFTP 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..283	CDD:238113	75/248 (30%)
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	73/245 (30%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	76/251 (30%)
		Tryp_SPc	34..267	CDD:238113	78/254 (31%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587603
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840