Protein Alignment CG18478 and Prss22

DIOPT Version :10

• Sequence 1: NP_609764.1
• Gene: CG18478 / 34923
• FlyBaseID: FBgn0028517
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001100454.1
• Gene: Prss22 / 302971
• RGDID: 1310880
• Length: 307
• Species: Rattus norvegicus
• Alignment Length: 300
• Identity: 88/300 - (29%)
• Similarity: 149/300 - (49%)
• Gaps: 41/300 - (13%)

  Fly     6 TLIVALFVLGVAE-NVENLQQIEELKCGYGNPDAVK-VQFNVTEG--QAKPAEFPWTIAVIHNRS 66
            |||:.:.:...|. :..|::         |:||..| .|.|...|  .:..|::||.::::.|.|
  Rat    17 TLILLVLLTSTATVSAANIR---------GSPDCGKPQQLNRVVGGEDSADAQWPWIVSILKNGS 72

  Fly    67 LVGGGSLITPDIVLTAAHRIFNKDVE---DIVVSAGEWEYGSALEKYPFEEAFVLKMVIHKSFNY 128
            ....|||:|...|::||| .|:.:::   ...|..|.|:.|:...:  .::..:..::.|..::.
  Rat    73 HHCAGSLLTNRWVVSAAH-CFSSNMDKPSPYSVLLGAWKLGNPGPR--SQKVGIASVLPHPRYSR 134

  Fly   129 QRGAN-NLALLFLDREFPLTYKINTICLPTQKRSL-SSTRCIVAGWGKYQFSDTHYGGV------ 185
            :.|.: ::||:.|:|....:.:|..||||.....| .:|.|.:||||..|      .||
  Rat   135 KEGTHADIALVRLERPIQFSERILPICLPDSSVHLPPNTNCWIAGWGSIQ------DGVPLPRPQ 193

  Fly   186 -LKKIDLPIVPRHICQDQLRKTRLGQNYTLPRGLICAGG-EKDNDACTGDGGGALFCPMTEDPKQ 248
             |:|:.:||:...:|: .|.....||. .:...::|||. |...|||.||.||.|.|.:.:   .
  Rat   194 TLQKLKVPIIDPELCK-SLYWRGAGQE-AITEDMLCAGYLEGKRDACLGDSGGPLMCQVDD---H 253

  Fly   249 FEQIGIVNWGVGCKEKNVPATYTDVFEFKPWIVQQIKENL 288
            :...||::||.||.|:|.|..||.:...:|| ||:|.:.:
  Rat   254 WLLTGIISWGEGCAERNRPGVYTSLLAHRPW-VQRIVQGV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	72/242 (30%)
Prss22	NP_001100454.1	Tryp_SPc	50..288	CDD:238113	76/252 (30%)