DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18478 and PRSS55

DIOPT Version :9

Sequence 1:	NP_609764.1	Gene:	CG18478 / 34923	FlyBaseID:	FBgn0028517	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_940866.2	Gene:	PRSS55 / 203074	HGNCID:	30824	Length:	352	Species:	Homo sapiens

Alignment Length:	253	Identity:	81/253 - (32%)
Similarity:	125/253 - (49%)	Gaps:	30/253 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VTEG-QAKPAEFPWTIAVIHNRSLVGGGSLITPDIVLTAAHRIFNKDV--EDIVVSAGEWEYGSA 106
            :|.| :|:..||||.:::........|||::....:|||||.::::::  |::.|..|.    :.
Human    68 ITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGT----ND 128

  Fly   107 LEKYPFEEAFVLKMVIHKSFNYQRGANNLALLFLDREFPLTYKINTICLPTQKRSLSSTRCIVAG 171
            |.....|...|..:::||.|......|::|||.|.....|......||||||....:...|.|||
Human   129 LTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAG 193

  Fly   172 WGKYQFSDTHYGGVLKKIDLPIVPRHI-----CQDQLRKTRLGQNYTLPRGLICAGGEKDN-DAC 230
            ||:...:|.:    ..|.||...|..|     |.....|        |.:.::|||.:.:: |||
Human   194 WGQTNAADKN----SVKTDLMKAPMVIMDWEECSKMFPK--------LTKNMLCAGYKNESYDAC 246

  Fly   231 TGDGGGALFCPMTEDP-KQFEQIGIVNWGVGCKEKNVPATYTDVFEFKPWI--VQQIK 285
            .||.||.|.|  |.:| :::.|:||::||..|.|||.|..||.:..:..||  |.|::
Human   247 KGDSGGPLVC--TPEPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLE 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..283	CDD:238113	78/243 (32%)
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	75/238 (32%)
PRSS55	NP_940866.2	Tryp_SPc	67..295	CDD:214473	77/244 (32%)
		Tryp_SPc	68..298	CDD:238113	79/247 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	308..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910