Protein Alignment CG18478 and Klk1b4

DIOPT Version :10

• Sequence 1: NP_609764.1
• Gene: CG18478 / 34923
• FlyBaseID: FBgn0028517
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_035045.2
• Gene: Klk1b4 / 18048
• MGIID: 97320
• Length: 256
• Species: Mus musculus
• Alignment Length: 287
• Identity: 81/287 - (28%)
• Similarity: 124/287 - (43%)
• Gaps: 67/287 - (23%)

  Fly    29 LKCGYGNPDA---VKVQFNVTEGQAKPAEFPWTIAVIHNRSLVGGGSLITPDIVLTAAHRIFNKD 90
            |....|..||   |:.|.:....|      ||.:||........||.|:..:.|||||| .:|..
Mouse     8 LALSLGGIDAAPPVQSQVDCENSQ------PWHVAVYRFNKYQCGGVLLDRNWVLTAAH-CYNDK 65

  Fly    91 VEDIVVSAGEWEYGSALEKYPFEE-AFVLKMVIHKSFN--------------YQRGANNLALLFL 140
            .:   |..|:   .:.||..|.:: ..|.|.:.|..||              |   :|:|.||.|
Mouse    66 YQ---VWLGK---NNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDY---SNDLMLLRL 121

  Fly   141 DREFPLTYKINTICLPTQKRSLSSTRCIVAGWG-----KYQFSDTHYGGVLKKIDLPIVPRHICQ 200
            .:...:|..:..|.|||::..|.|| |:.:|||     |:::.|.     |:.::|.::|...|
Mouse   122 SKPADITDVVKPITLPTEEPKLGST-CLASGWGSTTPIKFKYPDD-----LQCVNLKLLPNEDC- 179

  Fly   201 DQLRKTRLGQNYTLPRGLICAGGEKDNDA--CTGDGGGALFCPMTEDPKQFEQI--GIVNWG-VG 260
            |:..:.::..      .::|| ||.|..:  |..|.||.|.|         :.|  ||.:|| ..
Mouse   180 DKAHEMKVTD------AMLCA-GEMDGGSYTCEHDSGGPLIC---------DGILQGITSWGPEP 228

  Fly   261 CKEKNVPATYTDVFEFKPWIVQQIKEN 287
            |.|...|:.||.:.:|..||.:.:..|
Mouse   229 CGEPTEPSVYTKLIKFSSWIRETMANN 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	71/254 (28%)
Klk1b4	NP_035045.2	Tryp_SPc	13..251	CDD:238113	79/276 (29%)
		Activation peptide homolog	18..24		1/5 (20%)