DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18478 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_609764.1	Gene:	CG18478 / 34923	FlyBaseID:	FBgn0028517	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	283	Identity:	76/283 - (26%)
Similarity:	117/283 - (41%)	Gaps:	51/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NVENLQQIEELKCGYGNPDAVKVQFNVTEG-----QAKPAEFPWTIAVIHNRSLVGGGSLITPDI 78
            |.:.|.......||.       :..|.:.|     .:....:||..::........|||||..:.
Zfish   285 NSQALDSPSAAVCGI-------IPVNSSNGTVGGQNSSAVHWPWQASLYWYSGQTCGGSLINKEW 342

  Fly    79 VLTAAHRIFN--KDVEDIVVSAGEWEYGSALEKY-PFEEAFVLKMVI-HKSFNYQRGANNLALLF 139
            ||:||| .||  ::...:.|..|.    ....|| |...:..:|.|| |..:|.....|::||:.
Zfish   343 VLSAAH-CFNGQRNGFYLTVILGP----KTQNKYDPSRISRSVKAVIKHPYYNPNTNDNDIALVR 402

  Fly   140 LDREFPLTY--KINTICLPTQKRSLSS-TRCIVAGWGKYQFSDTHYGGV-------LKKIDLPIV 194
            |  .||:|:  .|..:||..:....:| |...:..|  ...||    ||       .:::::|::
Zfish   403 L--SFPITFTDSIRPVCLAAEGSVFNSDTESWITTW--RNISD----GVPLPSPKIFQEVEVPVI 459

  Fly   195 PRHICQDQLRKTRLGQNYTLPRGLICAGGEKD-NDACTGDGGGALFCPMTEDPKQ-FEQIGIVNW 257
            ....|........:..|      :||||..|: .|.|.||.||    ||..:... :.|.|||::
Zfish   460 GNRQCNCLYGVGSITDN------MICAGLLKEGKDLCQGDSGG----PMVSNQSSVWVQSGIVSF 514

  Fly   258 GVGCKEKNVPATYTDVFEFKPWI 280
            |.||.:...|..||.|..::.||
Zfish   515 GSGCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18478	NP_609764.1	Tryp_SPc	50..283	CDD:238113	70/247 (28%)
CG18478	NP_609764.1	Tryp_SPc	50..280	CDD:214473	68/245 (28%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035
		Tryp_SPc	309..537	CDD:238113	68/250 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587604
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930