DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18477 and prss60.1

DIOPT Version :9

Sequence 1:	NP_609763.1	Gene:	CG18477 / 34922	FlyBaseID:	FBgn0028864	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	342	Identity:	90/342 - (26%)
Similarity:	143/342 - (41%)	Gaps:	78/342 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 CVSTAICCPKNLIIKEPRLIIN----EPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVAL 124
            |||.|:.    |.::.....:|    .|:.:...|.||               |.:...||.|:|
Zfish     6 CVSLALL----LCVQGSHSQLNVCGLAPLNNRIVGGVN---------------AFDGSWPWQVSL 51

  Fly   125 LDARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQ----LPSVDVPIRSI 185
            .......:..||:||....|:||......:|.|.|:|      |..||.|    ...::..:..|
Zfish    52 HSPIYGGHFCGGSLINSEWVLTAAHCLPRITTSSLLV------FLGKTTQQGVNTYEINRTVSVI 110

  Fly   186 VRHPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDF---SRCIFTGWG--KNSFDDP 245
            ..||.:|.....|::||:.|..::|.|.:|.|:|:  |.:|..|   :....||||  :...:.|
Zfish   111 TVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCL--AAQNSVFPNGTSSWITGWGNIQLGVNLP 173

  Fly   246 SYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPGKDSCEGDGGSPLA---CAI 306
            : ..:|::..:|||....|...|     ....:.|:::||| .:.|:|:|:||.|.|:.   |.:
Zfish   174 A-PGILQETMIPVVPNDQCNALL-----GSGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLV 232

  Fly   307 KDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI------------------TLTTVNMPL 353
                  :..:||.::|..|..|..|.|||.|:....||                  |.::|:|.|
Zfish   233 ------WVQSGITSWGYGCADPYSPGVYTRVSQYQSWINSIIVQNLPGFVLFNSSSTCSSVSMTL 291

  Fly   354 PEE----REEVPYASPT 366
            |..    ...:..||||
Zfish   292 PNSTALPTSSISTASPT 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:214473	69/243 (28%)
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:238113	69/243 (28%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	72/265 (27%)
		Tryp_SPc	34..267	CDD:238113	74/267 (28%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587635
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840