DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18477 and prss60.2

DIOPT Version :9

Sequence 1:	NP_609763.1	Gene:	CG18477 / 34922	FlyBaseID:	FBgn0028864	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	300	Identity:	83/300 - (27%)
Similarity:	134/300 - (44%)	Gaps:	54/300 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LGCVS-TAICCPKNLIIKEPRLIINEPITDPQCGFVNSKGVTFSFREEDTGLAQEAEVPWMVALL 125
            |.|.: |.:.|.|. .:.:..:....|:.....|.||               |.|...||.|:|.
Zfish     4 LTCATLTLLICVKG-SLSQLNVCGQAPLNSRIVGGVN---------------APEGSWPWQVSLQ 52

  Fly   126 DARTSSYVAGGALIAPHVVITARQRTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRSIVR--- 187
            ..|...:..||:||:...|:||......::.|.|||..|.     :|:|..:.....|::.:
Zfish    53 SPRYGGHFCGGSLISSEWVLTAAHCLPGVSESSLVVYLGR-----RTQQGVNTHETSRNVAKIIV 112

  Fly   188 HPGFNLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFS---RCIFTGWGKNSFDDPSYMN 249
            |..:|.....|::||:.|..::|.:.:|.|:|:  |.:|..:|   ....||||    |..:.:|
Zfish   113 HSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCL--AAQNSVYSAGTSSWITGWG----DVQAGVN 171

  Fly   250 -----VLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPGKDSCEGDGGSPLA---CA 305
                 :|::..:|||....|..||     ....:.|:::||| .:.|||:|:||.|.|:.   |.
Zfish   172 LPAPGILQETMIPVVANDRCNAQL-----GSGTVTNNMICAGLAKGGKDTCQGDSGGPMVTRLCT 231

  Fly   306 IKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWIT 345
            :      :..|||.::|..|..|..|.|||.|:....||:
Zfish   232 V------WIQAGITSWGYGCADPNSPGVYTRVSQYQSWIS 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:214473	72/245 (29%)
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:238113	72/245 (29%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	75/267 (28%)
		Tryp_SPc	34..267	CDD:238113	77/268 (29%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840