DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18477 and CG14760

DIOPT Version :9

Sequence 1:	NP_609763.1	Gene:	CG18477 / 34922	FlyBaseID:	FBgn0028864	Length:	464	Species:	Drosophila melanogaster
Sequence 2:	NP_610366.1	Gene:	CG14760 / 35802	FlyBaseID:	FBgn0033277	Length:	529	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	76/307 - (24%)
Similarity:	122/307 - (39%)	Gaps:	63/307 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 KEPRLIINEPITDP--------------------QCGFVNSKGVTFSFREEDTGLAQEAEVPWMV 122
            |..|::.:.|...|                    .||:.....:.....||    |...|.|.|.
  Fly   232 KRARIVSSYPTAAPSPGHGGGRFSCLVEAFQPTCSCGWSRIPRIASPTNEE----AVLHEFPPMA 292

  Fly   123 ALLDARTSSYVAGGALIAPHVVITARQ---RTENMTASQLVVRAGEWDFSTKTEQLPSVDVPIRS 184
            .:|..:......|.|:|....:::|..   ..|..:|::|.|..||.|.::..|...:....:.:
  Fly   293 GVLTKKHGKVFCGAAIIHHRYLLSAAHCFLGPETNSAAKLRVVVGEHDLASSFETFATQRYDLDA 357

  Fly   185 IVRHPGFNLENG--ANNVALVFLRRSLTSSRHINPICMPSAPKN------FDFSRCIFTGWGKNS 241
            ::.|..|:..:|  .|::|::..|.::..|:|:.|.|:|..|..      ....:.:..|||..|
  Fly   358 LILHEDFSQASGQPKNDIAMLKTRMAIVWSQHVGPACLPLQPGEDGQKLPLAGHQVVAAGWGTTS 422

  Fly   242 FDDPSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAGG---------EPGKDSCEGD 297
            :..|....:| |.:|.|:..|.|.|              :|..|||         .||:|:|:.|
  Fly   423 YGGPQTHRLL-KATLDVIDGRRCRQ--------------ALSSAGGLPPHTFCTYTPGRDTCQYD 472

  Fly   298 GGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
            .|..|...|..   |....|||:||..|... .|:|.|.||:.|:||
  Fly   473 SGGALYERING---RLMAVGIVSFGQACAAQ-QPSVNTRVASFIKWI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:214473	66/250 (26%)
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:238113	66/250 (26%)
CG14760	NP_610366.1	CUB	37..126	CDD:294042
		Tryp_SPc	281..516	CDD:238113	70/258 (27%)
		Tryp_SPc	281..515	CDD:214473	68/256 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100