Protein Alignment CG18477 and PRSS50

DIOPT Version :10

• Sequence 1: NP_609763.1
• Gene: CG18477 / 34922
• FlyBaseID: FBgn0028864
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 399
• Identity: 98/399 - (24%)
• Similarity: 165/399 - (41%)
• Gaps: 78/399 - (19%)

  Fly     3 SMYGIIAIVSLILVA----GQVQAQGQNAELNQSCGASNEHQCVPRHMCKVKIEFRMAMTYRNLG 63
            |..|.:.::.|:|.:    |..:|.|   .|:.:..|....||||:..|.       :...|.|.
Human    20 SRAGALLLLLLLLRSAGCWGAGEAPG---ALSTADPADQSVQCVPKATCP-------SSRPRLLW 74

  Fly    64 CVSTAICCPKNLIIKEPRLIINEPITDP--QCGFVNSKGVTFSFREEDTGLAQEAEV---PWMVA 123
            ...|....|...:  |.:..::|...||  .||        ||:.::.|....||..   ||||:
Human    75 QTPTTQTLPSTTM--ETQFPVSEGKVDPYRSCG--------FSYEQDPTLRDPEAVARRWPWMVS 129

  Fly   124 LLDARTSSYVAGGALIAPHVVITARQRTENMTASQLV-------VRAGE-W-DFSTKTEQLPSVD 179
            :  ....:::..|.:||...|:|        .|..|:       ||.|. | |..|:|    :.|
Human   130 V--RANGTHICAGTIIASQWVLT--------VAHCLIWRDVIYSVRVGSPWIDQMTQT----ASD 180

  Fly   180 VPIRSIVRHPGFNLE------NGANNVALVFLRRSLTSSRHINPICMPSAPKNF-DFSRCIFTGW 237
            ||:..::.|..:..:      ..||::.|:.|::.|..|.::.|||:|...... |.|||..|||
Human   181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGW 245

  Fly   238 GKNSFDD--PSYMNVLKKISLPVVQRRTCEQQLRLYYGNDFE-------LDNSLMCAGGEPGKDS 293
            |.:..|.  |.:..:.:| .:.::..:.|:.    :|.|..:       :.:.:|||.....:..
Human   246 GLSKADGMWPQFRTIQEK-EVIILNNKECDN----FYHNFTKIPTLVQIIKSQMMCAEDTHREKF 305

  Fly   294 CEGDGGSPLACAIKDNPQRYELAGIVNFGVDCGLPGVPAVYTNVANVIEWI--TLTTVNMPLPEE 356
            |....|.||.|:::..   :.|.|:|::|..|.....|.:|..|::...||  .|....:.||..
Human   306 CYELTGEPLVCSMEGT---WYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQALALPAP 367

  Fly   357 REEVPYASP 365
            ...:..|.|
Human   368 SRTLLLALP 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:214473	64/258 (25%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	64/256 (25%)