Protein Alignment CG18477 and PRSS21

DIOPT Version :10

• Sequence 1: NP_609763.1
• Gene: CG18477 / 34922
• FlyBaseID: FBgn0028864
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 88/289 - (30%)
• Similarity: 140/289 - (48%)
• Gaps: 46/289 - (15%)

  Fly    77 IKEPRLIINEPITDPQCG--FVNSKGVTFSFREEDTGLAQEAEV---PWMVALLDARTSSYVAGG 136
            :::|......|::.| ||  .:.|:.|.          .::||:   ||..:|  ....|:|.|.
Human    18 LRKPESQEAAPLSGP-CGRRVITSRIVG----------GEDAELGRWPWQGSL--RLWDSHVCGV 69

  Fly   137 ALIAPHVVITARQRTENMTASQLVVRAGEW--DFSTKTEQLPS--------VDVPIRSIVRHPGF 191
            :|::....:||....|  |.|.|...:| |  .|...| .:||        ....:.:|...|.:
Human    70 SLLSHRWALTAAHCFE--TYSDLSDPSG-WMVQFGQLT-SMPSFWSLQAYYTRYFVSNIYLSPRY 130

  Fly   192 NLENGANNVALVFLRRSLTSSRHINPICMPSAPKNFDFSR---CIFTGWGKNSFDD--PSYMNVL 251
             |.|...::|||.|...:|.::||.|||:.::  .|:|..   |..||||....|:  || .:.|
Human   131 -LGNSPYDIALVKLSAPVTYTKHIQPICLQAS--TFEFENRTDCWVTGWGYIKEDEALPS-PHTL 191

  Fly   252 KKISLPVVQRRTCEQQLRLYYGNDFELDNSLMCAG-GEPGKDSCEGDGGSPLACAIKDNPQRYEL 315
            :::.:.::....| ..|.|.|....::...::||| .:.|||:|.||.|.||||  ..|...|::
Human   192 QEVQVAIINNSMC-NHLFLKYSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLAC--NKNGLWYQI 253

  Fly   316 AGIVNFGVDCGLPGVPAVYTNVANVIEWI 344
             |:|::||.||.|..|.||||:::..|||
Human   254 -GVVSWGVGCGRPNRPGVYTNISHHFEWI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18477	NP_609763.1	Tryp_SPc	113..344	CDD:214473	79/249 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	82/264 (31%)