Protein Alignment stol and yfbK

DIOPT Version :10

• Sequence 1: NP_001188817.2
• Gene: stol / 34921
• FlyBaseID: FBgn0028863
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: NP_416773.1
• Gene: yfbK / 946743
• ECOCYCID: G7177
• Length: 575
• Species: Escherichia coli
• Alignment Length: 677
• Identity: 122/677 - (18%)
• Similarity: 229/677 - (33%)
• Gaps: 233/677 - (34%)

  Fly    98 RNAVMRLMDS------------------------------AEQAALSELEGQGQAESPMGGQQHY 132
            :|.:|.||.|                              |:|||:.|.|....|...:..|:
E. coli     4 KNIIMLLMSSLILSGCGPQPENKESQQQQPSTPTEQQVLAAQQAAIKEAEQSAAAAKALAQQE-- 66

  Fly   133 DARRINEYNADGKLADGARHMDIRFMRRFERLPVNLSLSSILVPHGVD--------LDEPDVKSA 189
                :.:| :|.:...|          |.:..|.....:.....|..:        .|:..||..
E. coli    67 ----VQQY-SDKQALQG----------RLQEAPTFARAAKAKATHIANPGTARYQQFDDNPVKQV 116

  Fly   190 LQWSGHLDPLFQNNLEQDPALSWQYFGSSTGFLRRF--PGTAWPPEGSKGSKLIHDFRTHNWFVQ 252
            .|     :||...:|:.|.        .|...:|||  .|...||:..:..::::.|.: :|.::
E. coli   117 AQ-----NPLATFSLDVDT--------GSYANVRRFLNQGLLPPPDAVRVEEIVNYFPS-DWDIK 167

  Fly   253 -----AASSP---------------------------KD----------IMILLDASSSM-TEKS 274
                 .||.|                           ||          ::.|:|.|.|| :::.
E. coli   168 DKQSIPASKPIPFAMRYELAPAPWNEQRTLLKVDILAKDRKSEELPASNLVFLIDTSGSMISDER 232

  Fly   275 FDLGMATAFNILDTLGEDDFVNLITFSEVVKTPVPCFKDRMVRATPDNIQEIKSAVKAIKLQDTA 339
            ..|..::...::..|.|.|.:.::|::...:..:|..       :..:..||.:|:.::..:.:.
E. coli   233 LPLIQSSLKLLVKELREQDNIAIVTYAGDSRIALPSI-------SGSHKAEINAAIDSLDAEGST 290

  Fly   340 NFTAGLEYAFSLLHKYNQSGAG---SQCNQAIMLITE-------STSESHKDVIKQYNWPHMPVR 394
            |..||||.|      |.|:..|   ...|: |:|.|:       ...:|.:.::|:..  ...|.
E. coli   291 NGGAGLELA------YQQATKGFIKGGINR-ILLATDGDFNVGIDDPKSIESMVKKQR--ESGVT 346

  Fly   395 IFTYLIGSDSGSRSNLHDMACSNKGFFVQINDYDEARRKVIDYALVMARPMIMYQADH---PVHW 456
            :.|:.:|:.:.:.:.:..:|....|.:..|:...|| :||::..:   |.|::..|..   .:.:
E. coli   347 LSTFGVGNSNYNEAMMVRIADVGNGNYSYIDTLSEA-QKVLNSEM---RQMLITVAKDVKAQIEF 407

  Fly   457 SPVFVAGKSGGLGRDSEYQRRLVTTVSTPVFDRRNHSVRVANLLGVVGTDVPIEEIRKVIPQHKL 521
            :|.:|          :||::        ..:::|...|...|...|...|:...  :.:....:|
E. coli   408 NPAWV----------TEYRQ--------IGYEKRQLRVEHFNNDNVDAGDIGAG--KHITLLFEL 452

  Fly   522 GPNGYSFIVDNNGRVLYHPDLR-PLGDANQYIDQLKPKYASVDITELELPETEFGNNNEPIEINK 585
            ..||....:|   ::.|.||.: ...|..:.:..||.::......|.:|.|...|..     ||
E. coli   453 TLNGQKASID---KLRYAPDNKLAKSDKTKELAWLKIRWKYPQGKESQLVEFPLGPT-----IN- 508

  Fly   586 NLLNEMRGDMIKPKEGETEFTVMNHYDDSKRVSTRTHRYFYGPIEDTPFTLAIVLPEKYGSHEFV 650
                                                     .|.||..|..|:.   .||
E. coli   509 -----------------------------------------APSEDMRFRAAVA---AYG----- 524

  Fly   651 SQQEIRHSRNNVTEYFKGDNWRVHPDW 677
              |::|.|     ||....:|:....|
E. coli   525 --QKLRGS-----EYLNNTSWQQIKQW 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stol	NP_001188817.2	VWA_N	130..230	CDD:462464	19/109 (17%)
		vWA_VGCC_like	245..428	CDD:238740	41/235 (17%)
		PDC2_MCP_like	511..643	CDD:350337	21/132 (16%)
		VGCC_alpha2	810..>1048	CDD:462488
yfbK	NP_416773.1	YfbK	110..430	CDD:441879	69/371 (19%)
		DUF3520	392..569	CDD:432277	41/238 (17%)