Protein Alignment CG4587 and cachd1

DIOPT Version :9

• Sequence 1: NP_001188817.2
• Gene: CG4587 / 34921
• FlyBaseID: FBgn0028863
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: XP_001334829.3
• Gene: cachd1 / 794807
• ZFINID: ZDB-GENE-100819-3
• Length: 1290
• Species: Danio rerio
• Alignment Length: 1134
• Identity: 232/1134 - (20%)
• Similarity: 383/1134 - (33%)
• Gaps: 384/1134 - (33%)

  Fly   184 PDVKS-ALQWSGHLDPLFQNNLEQDPALSWQYFGSSTGFLRRFPGTAWPPEGSKGSKLIHDFRTH 247
            |.|.| |......|:.:..:||:.:|.:.||||.|..|....||...:..:|:      .:.|:.
Zfish   170 PTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTLFPAHKFHCKGT------FEHRSR 228

  Fly   248 NWFVQAASSP--KDIMILLDASSSMTEKSFDLGMATAFNILDTLGEDDFVNLITFSEVVKTPV-- 308
            ..:| ||..|  |.|::::|..:|:||....:....|..||:::.|.|.::::|.::.|::..
Zfish   229 PVYV-AAVRPQSKHIVVIIDHGASVTETQLQIARDAALVILNSIDEHDKISVLTIADTVRSCSLD 292

  Fly   309 PCFKDRMVRATPDNIQEIKSAVKAIKLQDTA-NFTAGLEYAFSLLHKYNQSGAGSQCNQAIML-- 370
            .|:|..:..||.:..:::.:.:..||..|:: ....|.:.||.||.  |.|....|.....|:
Zfish   293 QCYKSFLSPATSETKRKMSTFISNIKASDSSTQHAVGFQKAFQLLR--NTSNVTRQLTNTDMMII 355

  Fly   371 -----ITESTSESHK-----DVIKQYNWPHM--PVRIFTYLIGSD--SGSR--SNLHDMACSN-- 417
                 ||...|..|:     ..:|:.| .|:  .|.|.||.:.:|  :|.:  :.|.|:|..|
Zfish   356 YLSSGITSRDSSEHEKRATLSAVKEEN-RHLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSL 419

  Fly   418 -------------KGFFVQINDYDEARRKVIDYALVMARPMIMYQADHPVHWSPVFVAGKSGGLG 469
                         ||..:.:|........|..:.:.:...||    |......|  .|.:.|.
Zfish   420 KYGVQDRSALPVVKGSMMVLNQLSNLETTVGRFYINLPNRMI----DVATFSLP--YADQMGD-- 476

  Fly   470 RDSEYQRRLVTTVSTPVFDRRNHSVRVAN-LLGVVGTDVPIEEIRKVIPQHKLGPNGYSFIVDNN 533
                   ..:.|||.|.:        ..| ||||||.||.:..|.:.:..::.....|:|::||.
Zfish   477 -------GFIMTVSRPCY--------FGNLLLGVVGVDVNLAYILEDVTYYQDSLASYTFLIDNK 526

  Fly   534 GRVLYHPDL-RP--LGDANQYIDQLK----PKYASVDITELELPETEFGNNNEPIEINKNL---L 588
            |..|.||.| ||  :.:|..:.|.:.    |.:..|....|.||   .|:....:.:|.:|   :
Zfish   527 GYTLMHPSLTRPYLMTEAPLHTDIIHYENIPGFPVVRQNILSLP---LGSQVIAVPVNSSLSWHM 588

  Fly   589 NEMRGDMIKPKEGETEFTVMNHYDDSKRVSTRTHRYFYGPIEDTPFTLAIVLPEKYGSHEFVSQQ 653
            |.:|    .|..            |:..||     |.:..::||.|.|.||.
Zfish   589 NRLR----DPNR------------DAYNVS-----YAWKLVQDTSFILCIVY------------- 619

  Fly   654 EIRHSRNNVTEYFKGDNWRVHPDWVYCEYNSVSDLEKERESSGEYSSRDQEPSFGSPEEQVLHFL 718
                               |.|:   .....:.:|.....|...|...|   ..|.| ...|||.
Zfish   620 -------------------VQPE---IPVKQLKNLNTAPSSKLLYHRLD---LLGQP-SSCLHFK 658

  Fly   719 SRAGRPGWKWMSVRPKSPQPHHNMHSGSNGGNAPGSSHFGS--QHQSS-QGSRKAEPYFCDRALL 780
            ..|            ....|...:.:||          |.|  :|.|. :..|..|.|   .|.|
Zfish   659 QLA------------TVESPTVMLSAGS----------FSSPYEHLSQPETKRMVEHY---TAYL 698

  Fly   781 QSLVRDAMVTDGLD---RNTTGSSSGKEDKHPIATLMAILKRQGYQKFVVATSFVATRSGLLRWI 842
            ....| .:...||.   ||...::|     |.....|::::......::| ..::||.:|:||..
Zfish   699 SDNTR-LIANPGLKSSVRNEVMATS-----HVTDEWMSLMEMSSLNCYIV-RRYIATPNGVLRIY 756

  Fly   843 DHVKRPEDTPEPHFSEDNVRAMDTSWYKRAIDQHSVEPDSFVYSVPF----GSGYAIKSNATLVT 903
                 |....:..|  |..|   ..||..|:    ..|....::.|:    |:||       :||
Zfish   757 -----PGSLMDKAF--DPTR---RQWYLHAV----ANPGLITFTGPYLDVGGAGY-------VVT 800

  Fly   904 ASHAIFVEHRGHKAAAG----VVGLQFQHDSLAKHFINITSACTGMTGCKRTCASDNLDCYVLDN 964
            .||.|...  ..:.|:|    |:|:.|......|..:::...|....|.|       :.|:::::
Zfish   801 ISHTIHAP--SSQMASGYTVAVMGIDFTLRYFYKVLLDLLPICNQDKGNK-------IRCFIMED 856

  Fly   965 SGFVIISEEMEHTGKFFGQIDGTIMDSLVQDRIYKRVTVNDYQGVCSDADNPYTAAGGILKPNRL 1029
            .|:::                             ...|:.|.:|
Zfish   857 RGYLV-----------------------------AHPTLIDPKG--------------------- 871

  Fly  1030 GSWFFNHLLALSAAWLSLMPASLRAWPQEEYTYDNEDVVFVDNNYSDEYEFGNENEYNMQVDQEM 1094
                  |           .||.     |:..|:...   .|.|:..:...|..:|..|...|:.:
Zfish   872 ------H-----------APAE-----QQHITHKEP---LVANDILNHPNFVKKNLCNSFSDRTV 911

  Fly  1095 DEFFTTADVEYTTPPPRQHKPHVGPRFSPDPHNARRCDLRTDLYMLQPERLNQGGQNNPLKGKLT 1159
            ..|:                     :|                             |..:.|.||
Zfish   912 QRFY---------------------KF-----------------------------NTSIVGDLT 926

  Fly  1160 N-CHVSGCERPFSVQKIPHSNLILLVVDTLCPCGSKQLDIEPLEEAGVIGACSTRRQGQEQESRR 1223
            | .|.|.|.: :.:.:||.:|....:|:..|             :|....||||
Zfish   927 NLVHGSHCSK-YRLTRIPGTNAFAGIVNETC-------------DALAFCACST----------- 966

  Fly  1224 RPKKCINYHPEE-----------IEIQQC 1241
            ..:.|:|.|..|           :|:.:|
Zfish   967 VDRLCLNCHRMEQNECECPCECPLEVNEC 995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4587	NP_001188817.2	VWA_N	108..230	CDD:285584	16/46 (35%)
		vWA_VGCC_like	245..428	CDD:238740	54/220 (25%)
		Cache_1	456..544	CDD:280839	26/89 (29%)
		VGCC_alpha2	590..>647	CDD:285647	12/56 (21%)
cachd1	XP_001334829.3	VWA_N	102..217	CDD:285584	16/46 (35%)
		vWFA	226..>355	CDD:294047	34/131 (26%)
		Cache_1	469..536	CDD:280839	25/85 (29%)
		Cache_1	785..866	CDD:280839	20/125 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910