Protein Alignment CG4587 and stj

DIOPT Version :9

• Sequence 1: NP_001188817.2
• Gene: CG4587 / 34921
• FlyBaseID: FBgn0028863
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: NP_001246303.1
• Gene: stj / 36526
• FlyBaseID: FBgn0261041
• Length: 1271
• Species: Drosophila melanogaster
• Alignment Length: 1400
• Identity: 494/1400 - (35%)
• Similarity: 709/1400 - (50%)
• Gaps: 280/1400 - (20%)

  Fly     6 WSCFVA---IVLGVLIFKMHIFVAFA-----DQDEDIPHNEVRNWALKFGVDLWEFGRQFTKMNE 62
            ||..:|   :.||:|    .:.|..|     ...|:|.:|.|.:||.|.|::|:..|...|:..|
  Fly     3 WSRLLAWWRLCLGLL----SVLVCLAPCVNLQPAENINYNLVHSWADKLGMELFHLGDFITRRKE 63

  Fly    63 IKSRFKDNDIEVKRKDGIILLRELAAEVKNFMDFKRNAVMRLMDSAEQAALSELEGQGQAESPMG 127
            ::..||  |.:|..::|..::..:|.|::..||.|.:||.|:||:||..|||.
  Fly    64 VQESFK--DAKVVSRNGASIVDSMAKEIEMMMDLKVSAVRRIMDTAENTALSH------------ 114

  Fly   128 GQQHYDARRINEYNADGKLADG---------ARHMD----------------IRFMRRFERLPVN 167
             |.....:..:.|:|...|..|         |..||                :.....|...|||
  Fly   115 -QNDMADKMFSYYSAKEMLEPGDPVPPIPTPAPDMDKDIGEPLIYVQPKVVVLEPRPEFHNTPVN 178

  Fly   168 LSLSSILVPHGVDLDEPDVKSALQWSGHLDPLFQNNLEQDPALSWQYFGSSTGFLRRFPGTAW-- 230
            .|:||:.||..|....|||..|:|||.:||.:|::|.:.||.||||:|||||||:|:||.:.|
  Fly   179 FSVSSVHVPVNVFDRAPDVIKAIQWSENLDQIFRDNYKNDPTLSWQFFGSSTGFMRQFPASKWRK 243

  Fly   231 --PPEGSKGSKLIHDFRTHNWFVQAASSPKDIMILLDASSSMTEKSFDLGMATAFNILDTLGEDD 293
              |.:       ::|.|..:|:::||:|||||:||:|.|.||..:..|:.......||||||.:|
  Fly   244 DVPVD-------LYDCRLRSWYMEAATSPKDIVILMDGSGSMLGQRLDIAKHVVNTILDTLGTND 301

  Fly   294 FVNLITFSEVVKTPVPCFKDRMVRATPDNIQEIKSAVKAIKLQDTANFTAGLEYAFSLLHKYNQS 358
            |||:.||.:.|...||||:|.:::|...||:|:|..::..:.:..||:||.|..||.||.:...|
  Fly   302 FVNIFTFDKEVSPVVPCFEDTLIQANLGNIRELKEGIELFRPKSIANYTAALTKAFELLEETKLS 366

  Fly   359 GAGSQCNQAIMLITESTSESHKDVIKQYNW---PHMPVRIFTYLIGSDSGSRSNLHDMACSNKGF 420
            ..|:|||||||:|.:...|::::|.:.:||   |:.|||:||||||.:..:..::..|||.|:|:
  Fly   367 SRGAQCNQAIMIIGDGAPENNREVFELHNWRDPPYKPVRVFTYLIGKEVANWDDIRWMACENQGY 431

  Fly   421 FVQINDYDEARRKVIDYALVMARPMIMYQADHPVHWSPVFVAGKSGGLG------RDSEYQR--- 476
            :|.::|..|.|..|::|..|||||:::.:.||||.||.|:...:...|.      ...|||:
  Fly   432 YVHLSDTAEVREMVLNYIPVMARPLVLGRHDHPVIWSQVYADIEDTKLSDYLWDINQCEYQKADV 496

  Fly   477 -------------------------------------RLVTTVSTPVFDRRNHSV---------- 494
                                                 :.:||||.|::|||.:::
  Fly   497 LEYWQVHDRMLEPSEMHRRKYRRMKETWNQPVDSNVYQFMTTVSMPIYDRRENALINLTTDINPA 561

  Fly   495 --------RVANLLGVVGTDVPIEEIRKVIPQHKLGPNGYSFIVDNNGRVLYHPDLRPLGDANQY 551
                    |:||:|||.||||||.||:|::....||.|||:|||.|||.||:|||.||:...  |
  Fly   562 AKINLQVTRIANILGVAGTDVPINEIKKLLSPFTLGVNGYAFIVTNNGYVLFHPDFRPIFQG--Y 624

  Fly   552 IDQLKPKYASVDITELELPETEFGNNNEPIEINKNLLNEMRGDMIKPKEGETEFTVMNHYDDSKR 616
            |  |||.|.|||:.|:||.:     ::.|......:|..:|..:|....|.....|.||:|:.||
  Fly   625 I--LKPAYNSVDMIEVELLD-----DDRPARDFNPVLMTIRDSIINQSTGSKWMLVKNHFDEMKR 682

  Fly   617 VSTRTHRYFYGPIEDTPFTLAIVLPEKYG-SH-EFVSQQEIRH---SRNNVTEYFKGDNWRVHPD 676
            |:....:|::..|:.|||||.|..||:|| || :..:.|||..   ...|:...|.|..|::|||
  Fly   683 VARVKRQYYWTAIKKTPFTLVISYPEQYGVSHMDIRADQEIHRISIKGTNLRSVFSGKRWKIHPD 747

  Fly   677 WVYCEYNSVSDLEKERESSGEYSSRDQEPSFGSPEEQVLHFLSRAGRPGWKWMSVRPKSPQPHHN 741
            |::|                ::|:|    :|.:||.::|:||.|...|||:|...|...| |.|.
  Fly   748 WLFC----------------KHSNR----TFKTPEIELLYFLERMSEPGWRWPGSRSAMP-PEHA 791

  Fly   742 MHSGSNGGNAPGSSHFGSQHQSSQGS----RKAEPYFCDRALLQSLVRDAMVTDGLDRNTTGSSS 802
            ....||              .||.|.    .:.|.|:|||.|:|:||.||.||.....||  |.:
  Fly   792 AAMFSN--------------NSSTGRYPSINEKESYYCDRQLMQALVFDARVTGWFSNNT--SFN 840

  Fly   803 GKEDK-----HPIATLMAILKRQGY-QKFVVATSFVATRSGLLRWID-HVKRPEDTPEPH-FSED 859
            .|:||     .|||.||.:|.|..: |:|.|..:|:||.|||.||.: |....|::.... ||::
  Fly   841 SKDDKGTSASSPIAVLMGLLPRNEFKQRFGVTVAFLATHSGLTRWHEFHSNAAEESGVGETFSQN 905

  Fly   860 NVRAMDTSWYKRAIDQHSVEPDSFVYSVPFGSGYAIKSNA-TLVTASHAIFVEHRGHKAAAGVVG 923
            |.||:|..|||||:|||.|..:||||||||.:|   :||: .|||||||:|....|..|.|.|||
  Fly   906 NTRAIDEIWYKRAVDQHFVREESFVYSVPFDAG---ESNSEILVTASHAVFHNEGGKTAPAAVVG 967

  Fly   924 LQFQHDSLAKHFINITSACTGMTGCKRTCASDNLDCYVLDNSGFVIISEEMEHTGKFFGQIDGTI 988
            .||||.:|.|.|.|||.         ..||.|:.|||:|||:|:||||..:..||:|||:::|.|
  Fly   968 FQFQHSALYKLFHNITG---------NACAVDDKDCYILDNNGYVIISTRVHETGRFFGEVNGAI 1023

  Fly   989 MDSLVQDRIYKRVTVNDYQGVCSDADNPYTAAGGILKP----NRLGSWFFNHLLALSAAWLSLMP 1049
            |..|:::.:|::|||.|||.||.::.|...|:..:|.|    .|:|.|..:     :|.|..:
  Fly  1024 MKRLLEENVYRQVTVYDYQAVCFESKNDNNASSMLLSPLFHLLRVGKWLLH-----TALWYIV-- 1081

  Fly  1050 ASLRAWPQEEYTYDNEDVVFVDNNYSDEYEFGNENEYNMQVDQEMDEFFTTADVEYTTPPPRQHK 1114
             .|..|...           |.::|:|.|...|:.|                     .|||..|.
  Fly  1082 -QLLQWAPG-----------VSSHYADMYGDSNDTE---------------------PPPPEPHP 1113

  Fly  1115 PH-----VGPRFSPDPH----------NARRCDLRTDLYMLQPERLNQGGQNNPLKGKLTNCHVS 1164
            .|     .|.....|.|          ..:.||::.|||.|..|:.|          .:.|....
  Fly  1114 DHHARNGNGHGKKDDDHWLRYLTLHRTRLKPCDMKRDLYTLFNEKDN----------VVYNMTAH 1168

  Fly  1165 GCERPFSVQKIPHSNLILLVVDTLCP-CGSKQLDIEPLE---EAGVIGACSTRRQGQEQESRRRP 1225
            .|||||.|..||.|||||||:|.||| .||..|.:.|..   ...|..:.:..:|.:| .:|.||
  Fly  1169 ACERPFVVLPIPFSNLILLVIDQLCPRDGSVVLTVNPQPIDYHLSVNDSLACYKQARE-FNRMRP 1232

  Fly  1226 KKCINYHPEEIEIQQCGRGSTLLHMSGSVIVAHLL 1260
            ..||:.|..|..|:.||:..::....|.:::.|:|
  Fly  1233 HSCISRHANESGIKLCGKACSVYANLGLLLLCHIL 1267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4587	NP_001188817.2	VWA_N	108..230	CDD:285584	50/146 (34%)
		vWA_VGCC_like	245..428	CDD:238740	79/185 (43%)
		Cache_1	456..544	CDD:280839	46/151 (30%)
		VGCC_alpha2	590..>647	CDD:285647	22/57 (39%)
stj	NP_001246303.1	VWA_N	107..241	CDD:285584	50/146 (34%)
		vWA_VGCC_like	253..439	CDD:238740	79/185 (43%)
		Cache_1	524..619	CDD:280839	39/94 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I4730
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	572	1.000	Inparanoid score	I1017
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110668at33208
OrthoFinder	1	1.000	-	-		FOG0000496
OrthoInspector	1	1.000	-	-		mtm6553
orthoMCL	1	0.900	-	-		OOG6_103783
Panther	1	1.100	-	-	P	PTHR10166
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X365
	9	8.970