Protein Alignment stol and LOC1280001

DIOPT Version :10

• Sequence 1: NP_001188817.2
• Gene: stol / 34921
• FlyBaseID: FBgn0028863
• Length: 1271
• Species: Drosophila melanogaster
• Sequence 2: XP_061512654.1
• Gene: LOC1280001 / 1280001
• VectorBaseID: AGAMI1_008187
• Length: 1524
• Species: Anopheles gambiae
• Alignment Length: 1081
• Identity: 197/1081 - (18%)
• Similarity: 346/1081 - (32%)
• Gaps: 407/1081 - (37%)

  Fly    70 NDIEVKRKDGIILLRELAAEVKNFMDFKR-------------NAVMRLMDSAEQAALSELEGQGQ 121
            ||:|:..:..:.|.|:|...:....:.:|             |.::      .....|||....:
Mosquito   148 NDVELLERIALKLTRKLNQTIAVIEELRRYIQTTGTKYGAKYNTLL------NPCPYSELINPWE 206

  Fly   122 AESPMGGQQHYDARR------INEYNADGKL---ADGARHMDIRFMRRFERLPVNLSLSSILVPH 177
            .|:|...|....:.:      ...|:|.|.:   ..||....:.....|...|.|
Mosquito   207 DEAPFDLQSFIQSTKQSNVSLTRPYSASGDILVSGGGANSSAVTGFLDFSAFPAN---------- 261

  Fly   178 GVDLDEPDVKSA---------------LQWSGHLDPLFQNNLEQDPALSW--QYFGSSTGFLRRF 225
             .|.|.|.::..               .:.|.|||..:         ||:  |::.||......:
Mosquito   262 -ADSDRPRIRVTDQTIDDNNANLQQLFAEHSAHLDEHY---------LSYRQQFYLSSLDHASAY 316

  Fly   226 PGTAWPPEGSKGSKLIHDFRTHNWFVQAASSPKDIMILLDASSSMTEKSFDLGMATAFNILDTLG 290
            ....:|.:|          |....|:.|..: |.::||||..:::|....::..|.:..:|..|.
Mosquito   317 KCHYYPRDG----------RLKALFLSAVRN-KHVLILLDVGNTITYDQLEVAKAISKFVLYLLN 370

  Fly   291 EDDFVNLITFSEVVKTPVPCF----KDRMVRATPDNIQEIKSAVKAI-KLQDTANFTAGLEYAF- 349
            |:|.|.::...:.|.|....|    .:|.||||.|....:...:.:: :.:.|.:..||.:|||
Mosquito   371 ENDRVAVVAVGQRVITSDDFFDCRAANRFVRATMDEKDRLVDFIDSLNRTKQTTDHAAGFQYAFD 435

  Fly   350 ---------------------------------SLLHKYNQSGAGSQ----CNQAIMLITESTSE 377
                                             ::|...::......    .|..::|:.|....
Mosquito   436 AFSDIYRTHDDEVPIVFLYLGRALLPASSVVPKAILQTIHEGQTRLPYPVIINSCLILLDEREVA 500

  Fly   378 SHKDVIKQYNWPHMPVRIFTYLIGSDSGSRSNLHDMACSNKGFFVQINDYD-EARRKVIDYALVM 441
            ..|.:|..              |.:.:.:|.|| .:.....|..|.|:.:. :|:|    :.:.:
Mosquito   501 QEKQLIAD--------------ISTQNYARYNL-SLVIYPAGKMVMISKHSFDAQR----FIVAL 546

  Fly   442 ARPMI---MYQADHPVHWSPVFVAGKSGGLGRDSEYQRRLVTTVSTPVFDRRNHSVRVANLLGVV 503
            ..|.:   .:..:|.....|.:          |:..|..|| |||.|           |...|:|
Mosquito   547 MEPFLSAGRFIEEHLRIHLPYY----------DASLQDTLV-TVSYP-----------AGTHGLV 589

  Fly   504 GTDVPIEEIRKVIPQHKLGPNGYSFIVDNNGRVLYHPDL-RPLGDANQYIDQLKPKYASVDITEL 567
            |.|:.:.::.:.:..::...:.|:|::|..|..:.||.. |||.        .:..:...:||.|
Mosquito   590 GVDLYLSDLVEHVAYYRQQDDSYAFLIDLQGNTIMHPSFPRPLA--------ARGSFYITNITRL 646

  Fly   568 ELPETEFGNNNEPIEINKNLLNEMRGDMIKPKEGETEFTVMNHYDDSKRVSTRTHRYF----YGP 628
            |  :..|.      ...|.:|.:..|::           .:|||.     :.||..|:    |..
Mosquito   647 E--QEHFA------PAFKRMLADPEGNL-----------RINHYG-----TNRTTMYYWKRVYSY 687

  Fly   629 IEDTPFTLAIVLPEKYGSHEFVSQ------------QEIRHSRNNVTEYFKGDNWRVHPDWVYCE 681
            |.....||.:..|:...:.:..|:            .|....||:|                  |
Mosquito   688 IVCIVRTLDVAEPDNSLTVDGASRILHAPIHYLHPGAETPDGRNSV------------------E 734

  Fly   682 YNSV---SDLEKERESSGEYSSRDQEPSFGSPEEQVLHFLSRAGRPGWKWMSVRPKSPQPHHNMH 743
            ||.:   |...|...|:..|...|..|    |:.|                  ||    |...:.
Mosquito   735 YNFIAASSITAKNLLSTLLYHRIDIFP----PQLQ------------------RP----PVEMLP 773

  Fly   744 SGSNGGNAPGSSHFGSQHQSSQGSRKAEPYFCDRALLQSLVRDAMVTDGLD-------------- 794
            ||.:|.                              |..||:...|.|...
Mosquito   774 SGGDGS------------------------------LCRLVKQLAVADASTLYLSASSFQSPFTH 808

  Fly   795 -RNTTGSSSGKE-DKHPIATLMAILKRQGYQKFV------------------------------- 826
             ||...:.:|:| :...|..:||.| |..|.|.:
Mosquito   809 IRNNREAGAGEEVNVRTIQNIMAYL-RDTYGKLLFANPGLQPDVRSDVLALLQILFDYQLHHVQS 872

  Fly   827 -----VATSFVATRSGLLRW---------IDHVKRPEDTPEPHFSEDNVRAMDTSWYKRAIDQHS 877
                 |...:.||.:|:|:.         ::..|||                   |:.:|::.
Mosquito   873 NLSRYVVRRYAATVNGVLQTFPGGLLDTDLEPTKRP-------------------WFVKAMEY-- 916

  Fly   878 VEPDSFVYSVPF----GSGYAIKSNATLVTASHAIFVEHRG----------HKAAAGVVGLQFQH 928
              |...|::.|:    |:||       :|:.::|||....|          |:..| ||.|.|..
Mosquito   917 --PGRLVFTQPYLDAGGAGY-------VVSVAYAIFEGRTGGTATPSGNTPHRPIA-VVALDFTQ 971

  Fly   929 DSLAKHFINITSACTGMTGCKRTCASDNLDCYVLDNSGFVI 969
            ....|..::..:          .|:.||:.|:::|:.|:::
Mosquito   972 AFFYKLLLDSAT----------VCSMDNIKCFLMDDRGYLV 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stol	NP_001188817.2	VWA_N	130..230	CDD:462464	20/125 (16%)
		vWA_VGCC_like	245..428	CDD:238740	43/225 (19%)
		PDC2_MCP_like	511..643	CDD:350337	28/136 (21%)
		VGCC_alpha2	810..>1048	CDD:462488	41/219 (19%)
LOC1280001	XP_061512654.1	None