DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18480 and lrrc38b

DIOPT Version :9

Sequence 1:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	XP_021335529.1	Gene:	lrrc38b / 799882	ZFINID:	ZDB-GENE-141216-65	Length:	291	Species:	Danio rerio

Alignment Length:	248	Identity:	75/248 - (30%)
Similarity:	102/248 - (41%)	Gaps:	52/248 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LQCVTKPKMWLGLKQILLYVGLLLCVLLQVCRSKTQSQMFCPTVCHC-DLHAQRNRAVCSAKRLI 66
            |.||.:      |:.:|.   ||...||      ||.:. ||.:|.| |.|.    ..||.:.|.
Zfish     2 LPCVYR------LQPVLT---LLSFTLL------TQGEN-CPAICLCPDPHT----VDCSGRGLT 46

  Fly    67 SANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLSY 131
            ....|||..|..|.|:.|.|..|..|..                 .||.|       |.||||..
Zfish    47 RLPDEIPLDVRRLLLADNWIPRIPSDFL-----------------VLYSD-------LVYLDLRN 87

  Fly   132 NRLEQIDEHILESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRN----SQVNQLGTQLLSA 192
            |.|..|:...|.::::|:.|:|..|.|:.:.||....|.||..|.|.|    |.||:   .....
Zfish    88 NSLSNIEPGTLSTSSRLVFLDLGCNNLTEIPKGTFGESRSLIKLRLGNNPYLSMVNE---DAFMG 149

  Fly   193 LPQLRQLDLAQNLLLTLSPGDFHAPRNLASLNVEENPFNCDRALAKVATGLRQ 245
            |..||:|:|.:|.|..|..|......:|..:.:|.||:.|:...|.:.|.|.:
Zfish   150 LTSLRELELERNALSGLQVGALSQLPSLRVVRLEGNPWVCNCNFANLFTWLEE 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	16/59 (27%)
		LRR_RI	<76..230	CDD:238064	47/157 (30%)
		leucine-rich repeat	76..99	CDD:275380	7/22 (32%)
		leucine-rich repeat	100..123	CDD:275380	3/22 (14%)
		LRR_8	122..182	CDD:290566	23/63 (37%)
		leucine-rich repeat	124..147	CDD:275380	9/22 (41%)
		leucine-rich repeat	148..171	CDD:275380	8/22 (36%)
		LRR_8	170..230	CDD:290566	20/63 (32%)
		leucine-rich repeat	172..195	CDD:275380	8/26 (31%)
		leucine-rich repeat	196..219	CDD:275380	8/22 (36%)
lrrc38b	XP_021335529.1	LRRNT	26..56	CDD:214470	12/33 (36%)
		leucine-rich repeat	36..58	CDD:275380	8/25 (32%)
		PLN00113	<43..>185	CDD:331614	50/168 (30%)
		leucine-rich repeat	59..79	CDD:275380	8/36 (22%)
		leucine-rich repeat	80..103	CDD:275380	9/22 (41%)
		LRR_8	102..163	CDD:316378	22/63 (35%)
		leucine-rich repeat	104..127	CDD:275380	8/22 (36%)
		leucine-rich repeat	128..152	CDD:275380	8/26 (31%)
		leucine-rich repeat	153..176	CDD:275380	8/22 (36%)
		TPKR_C2	185..235	CDD:326558	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910