DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18480 and Lrtm2

DIOPT Version :9

Sequence 1:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001102900.1	Gene:	Lrtm2 / 680883	RGDID:	1587001	Length:	369	Species:	Rattus norvegicus

Alignment Length:	314	Identity:	86/314 - (27%)
Similarity:	118/314 - (37%)	Gaps:	69/314 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 WLGLKQILLYVGLLLCVLLQVCRSKTQSQMFCPTVCHCDLHAQRNRAVCSAKRLISANIEIPTTV 76
            |..|..|..::.|....:|..          ||..|.||                |.::|:
  Rat    18 WRQLSWITCWIALCAVEVLPA----------CPFSCTCD----------------SRSLEV---- 52

  Fly    77 ELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQIDEHI 141
               |.|...:||:..|....|..||   |.:|.:..|...||..|:.|:.||||.|.|:|:...:
  Rat    53 ---DCSGLGLTTVPPDVPAATQSLL---LLNNKLSALPSWAFANLSSLQRLDLSNNFLDQLPRSV 111

  Fly   142 LESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQNLL 206
            .:....|..|.|..|.:.||.:..:..||.||.|:|..:.:.||...|...|..||.|.|..|.|
  Rat   112 FQDLVNLTELQLRNNSIRTLDRDLLQHSPRLRHLDLSINGLAQLPQGLFDGLLALRSLSLRSNRL 176

  Fly   207 LTLSPGDFHAPRNLASLNVEENPFNCD------------------------RALAKVATGLRQRG 247
            .:|....|....:|..|.|.:||:.||                        ..|.|...|...|.
  Rat   177 QSLDRLTFEPLASLQLLQVGDNPWECDCNLREFKHWLEWFSYRGGRLDQLACTLPKELRGKDMRA 241

  Fly   248 VAIFMSN-CMEEEVQDHQD-DA------EAVNFPNKNEKFESMEYLEPSTRGPQ 293
            |.:.|.| |.:.|.::... ||      :|...|.|.:.....| .||||..||
  Rat   242 VPMEMFNYCSQLEDENSAGLDAPGPPCTKASPEPPKPKPGAEPE-PEPSTACPQ 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	20/59 (34%)
		LRR_RI	<76..230	CDD:238064	50/153 (33%)
		leucine-rich repeat	76..99	CDD:275380	6/22 (27%)
		leucine-rich repeat	100..123	CDD:275380	8/22 (36%)
		LRR_8	122..182	CDD:290566	20/59 (34%)
		leucine-rich repeat	124..147	CDD:275380	8/22 (36%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR_8	170..230	CDD:290566	21/59 (36%)
		leucine-rich repeat	172..195	CDD:275380	8/22 (36%)
		leucine-rich repeat	196..219	CDD:275380	8/22 (36%)
Lrtm2	NP_001102900.1	LRRNT	38..71	CDD:214470	12/65 (18%)
		leucine-rich repeat	51..93	CDD:275378	15/51 (29%)
		LRR_8	92..152	CDD:290566	20/59 (34%)
		LRR_4	93..132	CDD:289563	13/38 (34%)
		leucine-rich repeat	94..117	CDD:275378	8/22 (36%)
		LRR_4	117..156	CDD:289563	13/38 (34%)
		leucine-rich repeat	118..141	CDD:275378	7/22 (32%)
		LRR_8	140..199	CDD:290566	20/58 (34%)
		leucine-rich repeat	142..189	CDD:275378	16/46 (35%)
		leucine-rich repeat	166..186	CDD:275380	8/19 (42%)
		leucine-rich repeat	190..202	CDD:275378	5/11 (45%)
		TPKR_C2	198..247	CDD:301599	9/48 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000