DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG18480 and Aspn

DIOPT Version :9

Sequence 1:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_001165952.1 Gene:Aspn / 66695 MGIID:1913945 Length:373 Species:Mus musculus


Alignment Length:251 Identity:62/251 - (24%)
Similarity:105/251 - (41%) Gaps:63/251 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 CPTVCHCDLHAQRNRAV-CSAKRLISANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLA 106
            ||..|.|     .:|.| ||...|.|....||....::||..|.|..|.::.||....|..|.|.
Mouse    68 CPFGCQC-----YSRVVHCSDLGLTSVPNNIPFDTRMVDLQNNKIKEIKENDFKGLTSLYALILN 127

  Fly   107 HNAIHTLYGDAFVELTRLRYLDLSYNRLEQI--------------DE----------------HI 141
            :|.:..::...|:...:||.|.||:|:|.:|              |.                |:
Mouse   128 NNKLTKIHPKTFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHDNKVKKIQKDTFKGMNALHV 192

  Fly   142 LE------SNN----------QLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQLL 190
            ||      .||          .:.|:.:...||:::.||   ..|:|..|:|..::::.:..:.|
Mouse   193 LEMSANPLENNGIEPGAFEGVTVFHIRIAEAKLTSIPKG---LPPTLLELHLDFNKISTVELEDL 254

  Fly   191 SALPQLRQLDLAQNLLLTLSPGDF-HAPRNLASLNVEENPFNCDRALAKVATGLRQ 245
            ....:|::|.|..|.:..:..|.| :.|| :..:::|.|      .|.|:.:||::
Mouse   255 KRYRELQRLGLGNNRITDIENGTFANIPR-VREIHLEHN------KLKKIPSGLQE 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 18/59 (31%)
LRR_RI <76..230 CDD:238064 46/200 (23%)
leucine-rich repeat 76..99 CDD:275380 7/22 (32%)
leucine-rich repeat 100..123 CDD:275380 5/22 (23%)
LRR_8 122..182 CDD:290566 23/105 (22%)
leucine-rich repeat 124..147 CDD:275380 14/68 (21%)
leucine-rich repeat 148..171 CDD:275380 5/22 (23%)
LRR_8 170..230 CDD:290566 15/60 (25%)
leucine-rich repeat 172..195 CDD:275380 4/22 (18%)
leucine-rich repeat 196..219 CDD:275380 7/23 (30%)
AspnNP_001165952.1 LRRNT 68..97 CDD:214470 12/33 (36%)
leucine-rich repeat 77..96 CDD:275380 8/18 (44%)
LRR 1 96..117 6/20 (30%)
leucine-rich repeat 97..120 CDD:275380 7/22 (32%)
LRR_8 98..155 CDD:290566 18/56 (32%)
LRR 2 120..141 5/20 (25%)
leucine-rich repeat 121..144 CDD:275380 5/22 (23%)
LRR_RI <139..333 CDD:238064 39/175 (22%)
LRR 3 144..166 8/21 (38%)
leucine-rich repeat 145..165 CDD:275380 8/19 (42%)
Interaction with TGFB1 159..205 6/45 (13%)
leucine-rich repeat 166..189 CDD:275380 1/22 (5%)
LRR 5 189..212 5/22 (23%)
leucine-rich repeat 190..215 CDD:275380 5/24 (21%)
LRR_8 234..294 CDD:290566 15/66 (23%)
LRR 6 235..255 3/19 (16%)
leucine-rich repeat 236..259 CDD:275380 4/22 (18%)
LRR 7 259..280 6/20 (30%)
leucine-rich repeat 260..283 CDD:275380 6/22 (27%)
LRR 8 283..305 7/28 (25%)
LRR 9 306..327
leucine-rich repeat 307..331 CDD:275380
LRR 10 328..349
leucine-rich repeat 332..359 CDD:275380
LRR 11 350..373
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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