DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18480 and LRTM2

DIOPT Version :9

Sequence 1:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster
Sequence 2:XP_016875337.1 Gene:LRTM2 / 654429 HGNCID:32443 Length:427 Species:Homo sapiens


Alignment Length:328 Identity:88/328 - (26%)
Similarity:118/328 - (35%) Gaps:81/328 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MALQCVTKPKMWLGLKQILLYVGLLLCVLLQVCRSKTQSQMFCPTVCHCDLHAQRNRAVCSAKRL 65
            :|||       |..:..|..::.|.....|..          ||..|.||               
Human    71 LALQ-------WRQVSWITCWIALYAVEALPT----------CPFSCKCD--------------- 103

  Fly    66 ISANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLS 130
             |.::|:       |.|...:||:..|....|..||   |.:|.:..|...||..|:.|:.||||
Human   104 -SRSLEV-------DCSGLGLTTVPPDVPAATRTLL---LLNNKLSALPSWAFANLSSLQRLDLS 157

  Fly   131 YNRLEQIDEHILESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQLLSALPQ 195
            .|.|:::...|......|..|.|..|.:.||.:..:..||.||.|:|..:.:.||...|...|..
Human   158 NNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLA 222

  Fly   196 LRQLDLAQNLLLTLSPGDFHAPRNLASLNVEENPFNCD------------------------RAL 236
            ||.|.|..|.|..|....|....||..|.|.:||:.||                        ..|
Human   223 LRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTL 287

  Fly   237 AKVATGLRQRGVAIFMSN-CMEEEVQDHQDDA----------EAVNFPNKNEKFESMEYLEPSTR 290
            .|...|...|.|.:.|.| |  .:::|....|          :|...|.|.:.....| .||||.
Human   288 PKELRGKDMRMVPMEMFNYC--SQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPE-PEPSTA 349

  Fly   291 GPQ 293
            .||
Human   350 CPQ 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 20/59 (34%)
LRR_RI <76..230 CDD:238064 51/153 (33%)
leucine-rich repeat 76..99 CDD:275380 6/22 (27%)
leucine-rich repeat 100..123 CDD:275380 8/22 (36%)
LRR_8 122..182 CDD:290566 20/59 (34%)
leucine-rich repeat 124..147 CDD:275380 8/22 (36%)
leucine-rich repeat 148..171 CDD:275380 7/22 (32%)
LRR_8 170..230 CDD:290566 22/59 (37%)
leucine-rich repeat 172..195 CDD:275380 8/22 (36%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
LRTM2XP_016875337.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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