DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18480 and vasna

DIOPT Version :9

Sequence 1:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001313614.1	Gene:	vasna / 553185	ZFINID:	ZDB-GENE-050522-43	Length:	688	Species:	Danio rerio

Alignment Length:	619	Identity:	139/619 - (22%)
Similarity:	198/619 - (31%)	Gaps:	228/619 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LLLCVLLQVCRSKTQSQMFCPTVCHCDLHAQRNRAVCSAKRLISANIEIPTT------------- 75
            |:|..||..|.|..     ||..|.|   ...|...|..:.||.....:|:|
Zfish    10 LILLQLLCGCLSSR-----CPHDCTC---LPNNNIFCVQRNLIYMPRGLPSTGKQLYVFQNKINI 66

  Fly    76 -----------VELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDL 129
                       :|:||||.|.::.|.|..|.....|.||.|:.|.|..:..|:|:.|..|..|.|
Zfish    67 LQQQDFVELGELEMLDLSQNSLSEIPDGVFSPLSSLHNLDLSSNYITHISKDSFIGLVNLERLYL 131

  Fly   130 SYNRLEQIDEHILESNNQLIHLNLEGNKLSTL----------------GKGPI----LRSPSLRS 174
            ..|.::.|.....|....|:.|.|:||::|.|                ...|:    |::|.|.|
Zfish   132 YSNIIQNIHPAAFEGLENLLELKLQGNQISVLPALQLPRLLHLDLSYNSIPPLVAQDLQTPHLES 196

  Fly   175 LNLRNSQVNQLGTQLLSALPQLRQLDLAQNLLLTLSP---------------------------- 211
            |.:....:..|..:||.:|..|..||::||.|:.:.|
Zfish   197 LKIAGLGLTSLDEELLGSLVNLHVLDVSQNQLVDIQPTLKSMGGLRNLNLTGNPLGSLKHEDFQN 261

  Fly   212 -------------------GDFHAPRNLASLNVEENPFNCDRALAKVATGLRQRGVAIFMSNCME 257
                               |.|:....|..|...||||||...||.....|:...|.:..:
Zfish   262 LVNLLELDLSNLNLQGFPEGFFNLFPKLEKLTAAENPFNCLCPLAWFPAWLKDVRVELLRT---- 322

  Fly   258 EEVQDHQDDAEAVNFPNKN-----EKFESMEY------LEPSTRGPQSVLSVWR----------- 300
            ||.:.|        ||..|     ||.|..::      :|.::.|..|..|..:
Zfish   323 EETRCH--------FPPINSGKVLEKLEHKDFGCPTTTIELTSAGTSSTTSKPKNSSTQLGTTHI 379

  Fly   301 -------DLDSSEEQNSS--QDDEQMSSLSDVCEGSREKLCLRYRICLERVSHELLAGGNSQLED 356
                   |:.|::..|..  |.....|.:.:..||  |.:.....|||.        ||.
Zfish   380 VPPAPPSDISSADADNFPVYQTTAFPSRIMEDSEG--EGIMCPPNICLN--------GGT----- 429

  Fly   357 EIIRTHTYDEDDLKLAFVVGGATGVCMVIFIITFALCLKSC----CEMRKKKSNPEVATGVSAPL 417
                          ..|...|.. ||         ||..|.    ||::.:...|        |.
Zfish   430 --------------CIFKSNGVI-VC---------LCPPSMSGNYCEIQNEAMLP--------PP 462

  Fly   418 NPSQDSLPTIHTWSPQRTRNPRRSNPQRPRSTQSHAVVRQPYGPQDNFVSRLFGRPARSQYYRTI 482
            :| :.||.||.|              .:|.:..||.:.               ........:|.|
Zfish   463 SP-RVSLETIAT--------------VQPNTISSHHIT---------------STSISLDLHRYI 497

  Fly   483 NQNTATLIR--RLSRSNLFTSRDREPSSPAEPPT 514
              .|...||  ||:.||| :..||.|...:.||:
Zfish   498 --QTRPHIRGIRLTYSNL-SGPDRRPLQLSVPPS 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	23/83 (28%)
		LRR_RI	<76..230	CDD:238064	54/220 (25%)
		leucine-rich repeat	76..99	CDD:275380	9/22 (41%)
		leucine-rich repeat	100..123	CDD:275380	9/22 (41%)
		LRR_8	122..182	CDD:290566	19/79 (24%)
		leucine-rich repeat	124..147	CDD:275380	6/22 (27%)
		leucine-rich repeat	148..171	CDD:275380	9/42 (21%)
		LRR_8	170..230	CDD:290566	21/106 (20%)
		leucine-rich repeat	172..195	CDD:275380	7/22 (32%)
		leucine-rich repeat	196..219	CDD:275380	9/69 (13%)
vasna	NP_001313614.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000