DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18480 and LRRC52

DIOPT Version :9

Sequence 1:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_001005214.2 Gene:LRRC52 / 440699 HGNCID:32156 Length:313 Species:Homo sapiens


Alignment Length:269 Identity:68/269 - (25%)
Similarity:103/269 - (38%) Gaps:50/269 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 CPTVCHCDLHAQRNRAVCSAKRLISANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAH 107
            ||..|.|    |....:|:.|:|....::||.....|.|:.|.||::..........|:.|...:
Human    26 CPNNCLC----QAQEVICTGKQLTEYPLDIPLNTRRLFLNENRITSLPAMHLGLLSDLVYLDCQN 86

  Fly   108 NAIHTLYGDAFVELTRLRYLDLSYNRLEQIDEHILESNNQLIHLNLEGN-KLSTLGKGPILRSPS 171
            |.|..:....|:.:.:|.|||||.|.|..|........:.|:.||:..| .|.:|.|.....:.|
Human    87 NRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLSLHKFTFANTTS 151

  Fly   172 LRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQN---------------LLLTLSPG-DFHA---- 216
            ||.|:|||:.:..|.:..|..|..|..|.|:.|               ::..:.|. |.:|    
Human   152 LRYLDLRNTGLQTLDSAALYHLTTLETLFLSGNPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVE 216

  Fly   217 PRNLASLNVEE--NPFN--------------------CDRALAKVATGLRQRGV-AIFMSNCMEE 258
            |..|....:..  ||..                    |..|...||..|  .|| |:...|...:
Human   217 PTELTGWPITRVGNPLRYMCITHLDHKDYIFLLLIGFCIFAAGTVAAWL--TGVCAVLYQNTRHK 279

  Fly   259 EVQDHQDDA 267
            ..::.:|:|
Human   280 SSEEDEDEA 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 17/59 (29%)
LRR_RI <76..230 CDD:238064 46/176 (26%)
leucine-rich repeat 76..99 CDD:275380 5/22 (23%)
leucine-rich repeat 100..123 CDD:275380 5/22 (23%)
LRR_8 122..182 CDD:290566 23/60 (38%)
leucine-rich repeat 124..147 CDD:275380 9/22 (41%)
leucine-rich repeat 148..171 CDD:275380 7/23 (30%)
LRR_8 170..230 CDD:290566 20/81 (25%)
leucine-rich repeat 172..195 CDD:275380 9/22 (41%)
leucine-rich repeat 196..219 CDD:275380 8/42 (19%)
LRRC52NP_001005214.2 PRK15387 <2..>93 CDD:185285 19/70 (27%)
LRRNT 26..55 CDD:214470 10/32 (31%)
leucine-rich repeat 35..54 CDD:275380 5/18 (28%)
LRR 1 54..75 5/20 (25%)
leucine-rich repeat 55..78 CDD:275380 5/22 (23%)
LRR 2 78..99 5/20 (25%)
LRR_8 79..136 CDD:338972 17/56 (30%)
leucine-rich repeat 79..102 CDD:275380 5/22 (23%)
LRR 3 102..123 9/20 (45%)
leucine-rich repeat 103..126 CDD:275380 9/22 (41%)
LRR_8 126..185 CDD:338972 20/58 (34%)
LRR 4 126..148 7/21 (33%)
leucine-rich repeat 127..151 CDD:275380 7/23 (30%)
LRR 5 151..172 9/20 (45%)
leucine-rich repeat 152..175 CDD:275380 9/22 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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