DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18480 and CG18249

DIOPT Version :9

Sequence 1:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001163549.1	Gene:	CG18249 / 40964	FlyBaseID:	FBgn0037553	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	45/163 - (27%)
Similarity:	76/163 - (46%)	Gaps:	15/163 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 CSAKRLISANIEIPTTVELLDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRL 124
            |:...:...::.....:..|.:....:..:.|..|.....|..|.|:.|.|||::..||..|::|
  Fly    89 CATYHISKESLRPVENLTSLQMQGTSLGVLRDQIFNAVPRLEILQLSQNFIHTVHVAAFQGLSKL 153

  Fly   125 RYLDLSYNRLEQIDEHILESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQL 189
            |.|.|..|.:.:|....|:...:|:||:|..|:|:||.:....::..|::|.|..:.:..|...:
  Fly   154 RLLGLQGNAIAEILSSTLDPLMELVHLDLSRNELTTLPQNIFAKNKKLQTLLLNGNPLRILMPDV 218

  Fly   190 LSALPQLRQLDL---------------AQNLLL 207
            |.:||.||.|||               .|||:|
  Fly   219 LGSLPNLRLLDLGHAAELEVMTLNLTNVQNLVL 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	18/59 (31%)
		LRR_RI	<76..230	CDD:238064	44/147 (30%)
		leucine-rich repeat	76..99	CDD:275380	3/22 (14%)
		leucine-rich repeat	100..123	CDD:275380	10/22 (45%)
		LRR_8	122..182	CDD:290566	18/59 (31%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		leucine-rich repeat	148..171	CDD:275380	8/22 (36%)
		LRR_8	170..230	CDD:290566	16/53 (30%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	9/27 (33%)
CG18249	NP_001163549.1	leucine-rich repeat	57..80	CDD:275380
		LRR_8	104..163	CDD:290566	18/58 (31%)
		leucine-rich repeat	105..128	CDD:275380	3/22 (14%)
		LRR_RI	107..438	CDD:238064	44/145 (30%)
		leucine-rich repeat	129..152	CDD:275380	10/22 (45%)
		leucine-rich repeat	153..176	CDD:275380	7/22 (32%)
		LRR_8	176..232	CDD:290566	20/55 (36%)
		leucine-rich repeat	177..200	CDD:275380	8/22 (36%)
		leucine-rich repeat	201..224	CDD:275380	6/22 (27%)
		leucine-rich repeat	225..258	CDD:275380	9/27 (33%)
		leucine-rich repeat	259..310	CDD:275380
		leucine-rich repeat	311..344	CDD:275380
		LRR_8	343..403	CDD:290566
		leucine-rich repeat	345..368	CDD:275380
		leucine-rich repeat	369..390	CDD:275380
		leucine-rich repeat	393..417	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930