DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18480 and Lapsyn

DIOPT Version :9

Sequence 1:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_611561.1	Gene:	Lapsyn / 37418	FlyBaseID:	FBgn0034602	Length:	343	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	73/292 - (25%)
Similarity:	120/292 - (41%)	Gaps:	68/292 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QILLYVGLLLCVLLQVCRSK---TQSQMFCPTVCHCDLHAQRNRAVCSAKRLISANIEIPTTVEL 78
            |:|.::     |.||:..|.   .||::...|..|.|   :..|..|....|......:.::||:
  Fly     6 QLLTFI-----VCLQLLHSAGFIIQSEVRKCTYGHID---KLLRIRCYDLDLKEVPQNLKSSVEV 62

  Fly    79 LDLSYNDITTIDDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQIDEHILE 143
            ||||:|.|..:...||:....:..|.|..|.|.::....|..||.|:.:|||.|.|..|...:.:
  Fly    63 LDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILSVEVGTFEPLTSLQEIDLSNNGLTTIPLELFQ 127

  Fly   144 SNNQLIHLNLEGNKLSTLG----KGPILRSPSLRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQN 204
            . .:|.:|.::.|:|::|.    :.|| |:| |..||:...::.:|..  |..||:|.||:.:.|
  Fly   128 L-PRLRNLYIDSNELTSLNLQALEKPI-RAP-LEYLNVAGCELQELPD--LGILPKLWQLNASMN 187

  Fly   205 --------------------------------------LLLTLSPGDFHAPRNLASLNVEENPFN 231
                                                  ::|..||.  ..|..|.:|::.|.|..
  Fly   188 PLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLMMLGASPK--FVPVCLEALDIRECPLP 250

  Fly   232 CDRAL-----AKVATGLR---QRGVAIFMSNC 255
            .:|.:     |...|.|:   .|...:|.:.|
  Fly   251 YNRTIHSPTFASCQTTLQFAETRSFWLFGAGC 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	22/59 (37%)
		LRR_RI	<76..230	CDD:238064	51/195 (26%)
		leucine-rich repeat	76..99	CDD:275380	10/22 (45%)
		leucine-rich repeat	100..123	CDD:275380	6/22 (27%)
		LRR_8	122..182	CDD:290566	20/63 (32%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		leucine-rich repeat	148..171	CDD:275380	8/26 (31%)
		LRR_8	170..230	CDD:290566	19/97 (20%)
		leucine-rich repeat	172..195	CDD:275380	6/22 (27%)
		leucine-rich repeat	196..219	CDD:275380	8/60 (13%)
Lapsyn	NP_611561.1	leucine-rich repeat	39..59	CDD:275380	3/19 (16%)
		LRR_8	58..118	CDD:290566	22/59 (37%)
		leucine-rich repeat	60..83	CDD:275380	10/22 (45%)
		leucine-rich repeat	84..107	CDD:275380	6/22 (27%)
		LRR_RI	<94..>249	CDD:238064	38/161 (24%)
		LRR_8	106..167	CDD:290566	20/63 (32%)
		LRR_4	106..145	CDD:289563	12/39 (31%)
		leucine-rich repeat	108..130	CDD:275380	7/22 (32%)
		leucine-rich repeat	131..154	CDD:275380	7/23 (30%)
		leucine-rich repeat	157..178	CDD:275380	6/22 (27%)
		leucine-rich repeat	179..202	CDD:275380	4/22 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24366
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100