DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18480 and Lrg1

DIOPT Version :9

Sequence 1:	NP_001285960.1	Gene:	CG18480 / 34920	FlyBaseID:	FBgn0028518	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	XP_038939951.1	Gene:	Lrg1 / 367455	RGDID:	1359464	Length:	342	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	71/299 - (23%)
Similarity:	109/299 - (36%)	Gaps:	79/299 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GLLLCVLLQVCRSKTQSQMFCPTVCH---------------------------------C----D 50
            ||..|::||..:..|.|       ||                                 |    :
  Rat    32 GLRECLILQSVKGSTVS-------CHGPTEFPSSLPADTVHLSVEFSSLTQLPAAALQGCPGLQE 89

  Fly    51 LHAQRNRAVCSAKRLISANIEIPT-TVELLDLSYNDITTIDDDSFKTTIHLLNLT---------- 104
            ||...||.     :.:|..:..|. .:.:|||:.|.:.::....|:::..|..|.
  Rat    90 LHLSSNRL-----QELSPGLLAPVPRLRVLDLTRNALRSLPPGLFRSSAALNTLVLRENQLQEAS 149

  Fly   105 --------------LAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQIDEHILESNNQLIHLNLEG 155
                          ||.|.:.:|.......|..|..|||.:|.||.:.|..|....:|..|:|||
  Rat   150 ARWLQGLDALGYLDLAENRLRSLPARLLANLGALHTLDLGHNLLESLPEGFLRGPRRLQRLHLEG 214

  Fly   156 NKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQNLLLTLSPGDF----HA 216
            |:|..|..|.:...|.|..|.|.::|:..:.......|.||..|||:.|.|.:..||.:    ..
  Rat   215 NRLQRLEAGLLAPQPFLGVLFLNDNQLTAVAADSFRGLKQLDMLDLSNNSLSSTPPGLWAFLGRP 279

  Fly   217 PRNLA-SLNVEENPFNCDRALAKVATGLRQRGVAIFMSN 254
            .|::. ..:|..||:.||:.|..:...|......:|..|
  Rat   280 TRDMQDGFDVSHNPWVCDKDLVDLCRWLAANRHKMFSQN 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_001285960.1	LRR_8	74..134	CDD:290566	17/84 (20%)
		LRR_RI	<76..230	CDD:238064	48/182 (26%)
		leucine-rich repeat	76..99	CDD:275380	5/22 (23%)
		leucine-rich repeat	100..123	CDD:275380	7/46 (15%)
		LRR_8	122..182	CDD:290566	22/59 (37%)
		leucine-rich repeat	124..147	CDD:275380	9/22 (41%)
		leucine-rich repeat	148..171	CDD:275380	9/22 (41%)
		LRR_8	170..230	CDD:290566	18/64 (28%)
		leucine-rich repeat	172..195	CDD:275380	5/22 (23%)
		leucine-rich repeat	196..219	CDD:275380	8/26 (31%)
Lrg1	XP_038939951.1	PRK15370	<55..>293	CDD:185268	54/242 (22%)
		leucine-rich repeat	65..86	CDD:275380	1/20 (5%)
		leucine-rich repeat	87..110	CDD:275380	6/27 (22%)
		leucine-rich repeat	111..134	CDD:275380	5/22 (23%)
		leucine-rich repeat	135..158	CDD:275380	2/22 (9%)
		leucine-rich repeat	159..182	CDD:275380	5/22 (23%)
		leucine-rich repeat	183..206	CDD:275380	9/22 (41%)
		leucine-rich repeat	207..230	CDD:275380	9/22 (41%)
		leucine-rich repeat	231..254	CDD:275380	5/22 (23%)
		leucine-rich repeat	255..278	CDD:275380	8/22 (36%)
		PCC	259..>339	CDD:188093	16/60 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000