Protein Alignment CG18480 and kek4

DIOPT Version :10

• Sequence 1: NP_609761.1
• Gene: CG18480 / 34920
• FlyBaseID: FBgn0028518
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_609615.2
• Gene: kek4 / 34718
• FlyBaseID: FBgn0032484
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 125/565 - (22%)
• Similarity: 213/565 - (37%)
• Gaps: 111/565 - (19%)

  Fly    13 LGLKQILLYVGLLLCVLLQVCRSKTQSQMFCPTVCHCDLHAQRNRAVCSAKRLISANIEIPTTVE 77
            :.||.:.|::..:.|:.| :.||.:...:.....|||..::.:..|.|....|......:...|:
  Fly    12 ISLKHLSLFLFKIYCLAL-IFRSASADWLLDCGNCHCKWNSGKKTADCRNLSLSGVPEYLSPEVQ 75

  Fly    78 LLDLSYNDITTIDDDSFKTTIHLLN---LTLAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQIDE 139
            :||||:|.|..:::::|.|| ||.|   |.:.:..:..|...:|.:|..|..||||.|.|..:..
  Fly    76 VLDLSHNHIFYLEENAFLTT-HLQNLQKLLIRNGTLKYLNQRSFTQLQILIELDLSNNLLVDLLP 139

  Fly   140 HILESNNQLIHLNLEGNKLSTLGKGPILRSPSLRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQN 204
            ::.:..:::..:.|.||.|..|..|.......|..:.|:.:::..:..:....:|.|.|:.|..|
  Fly   140 NVFDCLSKVRAIFLNGNLLQALRHGVFRNLKYLHKIELKRNRLVSIDAKAFVGVPLLSQIYLDNN 204

  Fly   205 LLLTLSPGDFHAPRNLASLNVEENPFNCDRALAKVATGLRQRGVAIFMSNCMEEEVQDH------ 263
            .|..|....|.....|.:|::.|||:||...|...      |...|.| |........|
  Fly   205 ELTKLRVESFQDLTKLTALSLVENPWNCTCDLQMF------RDFVIGM-NLYTPPTSCHYPLQLR 262

  Fly   264 -----QDDAEA------VNFP----NKNEKFESMEYLEPSTRGPQSVLSVWRDLDSSEEQNSS-- 311
                 :|..||      :.:|    :.|...|::..:......|.:|:: |...:...|..|.
  Fly   263 GRLWIEDQPEAFACKPKIVYPTLSTSINTSKENVTLICRVHGSPNTVIA-WDYTNQVYESRSKPV 326

  Fly   312 -------------QDDEQMSSLSDVCEGSREKLCLRYRICLERVSHE----LLA---GGNSQLED 356
                         ::||     |.:.:...:....|..|...|.|.|    .||   ||...:..
  Fly   327 KSLQKQRIYIELLREDE-----SKIRKFGHDVFVSRLTIVNARKSDEGVYTCLAENPGGKDSVHI 386

  Fly   357 EII------RTHTYDEDDLKLAFVVGGATGVCMVIFIITFALCLKSCCEMRKKKSNPEVATGVSA 415
            .::      |....|.:...:..::  |.|...:..:.:...||   ...|.|:.:|    |...
  Fly   387 SVVVQKDMERISLIDSNFFAIVCLI--AMGFLSMSILFSLVTCL---IFKRFKQFHP----GQHT 442

  Fly   416 PLNPSQDSLPTIHTWSPQRTRNPRRSNPQRPRSTQSHAVVRQPYGPQDNFVSRLFGRPARSQY-- 478
            .|.|:  |||.....|.:.|          ..|..|..|:|:.....|...:  ...|:...|
  Fly   443 YLQPT--SLPVQSPGSEEAT----------AISALSSGVIRESKIVLDPLSA--INEPSNKNYTL 493

  Fly   479 YRTINQNTATLIR-------RLSRSNLFT-----------SRDRE 505
            ::|.|.|.:..:.       ||: ||.:|           ||:||
  Fly   494 FKTSNSNGSEYMHTRNYKDVRLN-SNTYTENLDNQAESISSRNRE 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18480	NP_609761.1	LRR	<66..>230	CDD:443914	44/166 (27%)
		leucine-rich repeat	76..99	CDD:275380	10/22 (45%)
		leucine-rich repeat	100..123	CDD:275380	6/25 (24%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..195	CDD:275380	2/22 (9%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
kek4	NP_609615.2	LRR	59..>228	CDD:443914	43/169 (25%)
		leucine-rich repeat	75..99	CDD:275380	11/24 (46%)
		LRR_8	98..158	CDD:404697	15/59 (25%)
		leucine-rich repeat	100..123	CDD:275380	4/22 (18%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		leucine-rich repeat	148..171	CDD:275380	6/22 (27%)
		leucine-rich repeat	172..195	CDD:275380	2/22 (9%)
		leucine-rich repeat	196..219	CDD:275380	7/22 (32%)
		LRRCT	228..277	CDD:214507	13/55 (24%)
		IG_like	294..390	CDD:214653	18/101 (18%)
		Ig strand B	296..300	CDD:409353	0/3 (0%)
		Ig strand C	309..323	CDD:409353	3/14 (21%)
		Ig strand E	356..360	CDD:409353	1/3 (33%)
		Ig strand F	370..375	CDD:409353	0/4 (0%)
		Ig strand G	383..386	CDD:409353	0/2 (0%)