DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18480 and haf

DIOPT Version :9

Sequence 1:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_001356954.1 Gene:haf / 33339 FlyBaseID:FBgn0261509 Length:1347 Species:Drosophila melanogaster


Alignment Length:501 Identity:115/501 - (22%)
Similarity:183/501 - (36%) Gaps:117/501 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 VELLDLSYNDITTIDDDSF-----KTTIHL--LNLTLAHNAIHTL----------------YGDA 117
            :.|||||.|.::.|.||:|     .:|:.|  .|:|||.||...|                ..::
  Fly   155 LNLLDLSKNQLSHIPDDAFVGLTKLSTLKLNDNNVTLASNAFRGLEQSLKNLNLKGTKQRKVPES 219

  Fly   118 FVELTRLRYLDLSYNRLEQIDE----HILESNNQLIHLNLEGNKLSTLGKGPI--LRSPSLRSLN 176
            ...|..|.:||||.|.::::..    .:.:..:.|..||||.|.:.::|:...  :|. :|.||:
  Fly   220 IRGLKSLAFLDLSQNGIKELPGAGGIRVFDGLDALTALNLERNLIQSIGETAFAGVRK-TLSSLS 283

  Fly   177 LRNSQVNQLGTQLLSALPQLRQLDLAQNLLLTLSPGDFHAPRNLASLNVEENPFNC--DRALAKV 239
            |.|:.:.:.....:.:|.:||.||:..|||.:|....|.....:..|.::.||.:.  :.|.|.:
  Fly   284 LLNNLLAEFPIGAVHSLKELRVLDIGFNLLTSLPEAAFRGNPGITLLALDGNPLSSVPEGAFAHL 348

  Fly   240 ATGLR--QRGVAIFMSNCMEEEVQDHQDDAEAVNFPNKNEKFESMEYLEPSTRGPQSVLSVWRDL 302
            ...||  ..|......:|....|      ||.:.  |.:.:..|.|      |.||...:..|..
  Fly   349 NATLRGLSLGGRFLHCDCKLRWV------AEWIR--NGDLQVTSRE------RNPQFCGTPPRFR 399

  Fly   303 DSSEEQNSSQDDEQMSSLSDVCEGSREKLCLRYRICLERVSHELLAGGNSQLEDEIIRTHTYDED 367
            |..  ..|.|.:|  .|..|:.:.:     ||               |...|.|.:..|.....|
  Fly   400 DRG--FYSIQPEE--LSCPDIADAA-----LR---------------GPVGLADNLKPTLPSSPD 440

  Fly   368 DLKLAFVVGGATGVCMVIFIITFALCLKSCCEMRKKKSNPEVATG--VSAPLNPSQDSLPTIHTW 430
            .::  :..|..||.                           |.||  .|||:..|..|  :..|.
  Fly   441 SVE--YETGTGTGT---------------------------VGTGTAASAPVTSSVSS--STSTT 474

  Fly   431 SPQRTRNPRRSNPQRPRSTQSHAVVRQPYGPQDNFVSRLFGRPARSQYYRTINQNTATLIRRLSR 495
            :|..|.....:.|...|||      .:|.......:|.....||.:..........||.|...|.
  Fly   475 TPTTTTTTTTAEPTTRRST------TRPPTKSTTTISATTASPASNPPVNGTGTVQATSITTSSS 533

  Fly   496 SNLFTSRDREPSSPAEPP-----TSTARFYTDVIESGAI-RPETPP 535
            |:..:|......:..:.|     .:.....:.|..:|.: :|:.||
  Fly   534 SSSSSSTSTGHGNGKQAPGWRQGVTNGNGNSGVGGAGGLHKPQRPP 579

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 26/80 (33%)
LRR_RI <76..230 CDD:238064 51/182 (28%)
leucine-rich repeat 76..99 CDD:275380 11/27 (41%)
leucine-rich repeat 100..123 CDD:275380 9/40 (23%)
LRR_8 122..182 CDD:290566 19/65 (29%)
leucine-rich repeat 124..147 CDD:275380 6/26 (23%)
leucine-rich repeat 148..171 CDD:275380 8/24 (33%)
LRR_8 170..230 CDD:290566 17/59 (29%)
leucine-rich repeat 172..195 CDD:275380 6/22 (27%)
leucine-rich repeat 196..219 CDD:275380 9/22 (41%)
hafNP_001356954.1 LRR <52..>252 CDD:227223 26/96 (27%)
leucine-rich repeat 86..105 CDD:275380
leucine-rich repeat 106..129 CDD:275380
LRR_8 131..189 CDD:338972 12/33 (36%)
leucine-rich repeat 131..154 CDD:275380
leucine-rich repeat 155..178 CDD:275380 10/22 (45%)
leucine-rich repeat 179..202 CDD:275380 9/22 (41%)
leucine-rich repeat 203..225 CDD:275380 1/21 (5%)
leucine-rich repeat 226..253 CDD:275380 6/26 (23%)
LRR_8 254..337 CDD:338972 25/83 (30%)
leucine-rich repeat 254..302 CDD:275380 14/48 (29%)
leucine-rich repeat 303..326 CDD:275380 9/22 (41%)
leucine-rich repeat 327..350 CDD:275380 5/22 (23%)
PCC 332..>413 CDD:188093 22/98 (22%)
PRK10927 <1061..>1097 CDD:236797
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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