DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG18480 and Igfals

DIOPT Version :9

Sequence 1:NP_001285960.1 Gene:CG18480 / 34920 FlyBaseID:FBgn0028518 Length:550 Species:Drosophila melanogaster
Sequence 2:NP_001351825.1 Gene:Igfals / 16005 MGIID:107973 Length:638 Species:Mus musculus


Alignment Length:244 Identity:66/244 - (27%)
Similarity:95/244 - (38%) Gaps:85/244 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 DLHAQRNRAVCSAKRLISAN--IEIPTTVEL-----------------------LDLSYNDITTI 89
            :|...||     |.|.:.||  |.:|...:|                       ||||:|.:..:
Mouse   257 ELDLSRN-----ALRSVKANVFIHLPRLQKLYLDRNLITAVAPRAFLGMKALRWLDLSHNRVAGL 316

  Fly    90 DDDSFKTTIHLLNLTLAHNAIHTLYGDAFVELTRLRYLDLSYNRLEQIDE---------HILESN 145
            .:|:|...:.|..|.||||||.:|....|.:|..|..|.|.:||:.|:.|         .:|..|
Mouse   317 LEDTFPGLLGLHVLRLAHNAITSLRPRTFKDLHFLEELQLGHNRIRQLGEKTFEGLGQLEVLTLN 381

  Fly   146 NQLIH---------------LNLEGNKLSTL------GKGPI------------LR------SPS 171
            :..||               :||.||.|.:|      |.|.:            :|      ...
Mouse   382 DNQIHEVKVGAFFGLFNVAVMNLSGNCLRSLPEHVFQGLGRLHSLHLEHSCLGRIRLHTFAGLSG 446

  Fly   172 LRSLNLRNSQVNQLGTQLLSALPQLRQLDLAQNLLLTLSPGDFHAPRNL 220
            ||.|.||::.::.:..|.|:.|.:|.:|||..|.|.       |.||.|
Mouse   447 LRRLFLRDNSISSIEEQSLAGLSELLELDLTANQLT-------HLPRQL 488

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18480NP_001285960.1 LRR_8 74..134 CDD:290566 23/82 (28%)
LRR_RI <76..230 CDD:238064 57/216 (26%)
leucine-rich repeat 76..99 CDD:275380 8/45 (18%)
leucine-rich repeat 100..123 CDD:275380 11/22 (50%)
LRR_8 122..182 CDD:290566 25/107 (23%)
leucine-rich repeat 124..147 CDD:275380 9/31 (29%)
leucine-rich repeat 148..171 CDD:275380 11/61 (18%)
LRR_8 170..230 CDD:290566 18/51 (35%)
leucine-rich repeat 172..195 CDD:275380 8/22 (36%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
IgfalsNP_001351825.1 LRRNT 75..113 CDD:214470
leucine-rich repeat 92..110 CDD:275380
PLN00113 96..>558 CDD:331614 66/244 (27%)
leucine-rich repeat 114..134 CDD:275380
leucine-rich repeat 135..158 CDD:275380
leucine-rich repeat 159..182 CDD:275380
leucine-rich repeat 183..206 CDD:275380
leucine-rich repeat 207..230 CDD:275380
leucine-rich repeat 231..254 CDD:275380
leucine-rich repeat 255..278 CDD:275380 8/25 (32%)
leucine-rich repeat 279..302 CDD:275380 1/22 (5%)
leucine-rich repeat 303..326 CDD:275380 7/22 (32%)
leucine-rich repeat 327..350 CDD:275380 11/22 (50%)
leucine-rich repeat 351..374 CDD:275380 7/22 (32%)
leucine-rich repeat 375..396 CDD:275380 4/20 (20%)
leucine-rich repeat 423..446 CDD:275380 1/22 (5%)
leucine-rich repeat 447..470 CDD:275380 8/22 (36%)
leucine-rich repeat 471..494 CDD:275380 10/25 (40%)
leucine-rich repeat 495..516 CDD:275380
leucine-rich repeat 519..542 CDD:275380
leucine-rich repeat 543..561 CDD:275380
TPKR_C2 570..613 CDD:326558
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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